Evidence map›Paper›PMID 36429527›Full record

ArticleInternational journal of environmental research and public health2022

Factors Influencing Cortisol Concentrations in Breastmilk and Its Associations with Breastmilk Composition and Infant Development in the First Six Months of Lactation.

Monika A Zielinska-Pukos, Joanna Bryś, Natalia Kucharz, Agnieszka Chrobak, Aleksandra Wesolowska, Iwona Grabowicz-Chądrzyńska, Jadwiga Hamulka

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07457515 (Analysis of the Transmission of Overweight/Obesity in the Mother-breastmilk-child Triad in Relation to Maternal Cardiometabolic Status and Diet), which is not on this map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07457515 not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Analysis of the Transmission of Overweight/Obesity in the Mother-breastmilk-child Triad in Relation to Maternal Cardiometabolic Status and Diet

TypeobservationalSponsorWarsaw University of Life SciencesRan2026 to 2029Enrolled165ConditionsBody Weight, Obesity & Overweight, Human Milk/Breastfeeding, Body Composition
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Monika A Zielinska-PukosDepartment of Human Nutrition, Institute of Human Nutrition Sciences, Warsaw University of Life Sciences-SGGW, Nowoursynowska St. 159, 02-776 Warsaw, Poland.ORCID 0000-0001-8894-6746
Joanna BryśDepartment of Chemistry, Institute of Food Sciences, Warsaw University of Life Sciences-SGGW, Nowoursynowska St. 159, 02-776 Warsaw, Poland.ORCID 0000-0002-7852-3624
Natalia KucharzHirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, 53-114 Wrocław, Poland.
Agnieszka ChrobakHirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, 53-114 Wrocław, Poland.
Aleksandra WesolowskaLaboratory of Human Milk and Lactation Research at Regional Human Milk Bank in Holy Family Hospital, Department of Neonatology, Faculty of Life Sciences, Medical University of Warsaw, Litewska 14/16 Str., 00-575 Warsaw, Poland.ORCID 0000-0002-7270-5910
Iwona Grabowicz-ChądrzyńskaPsychological-Pedagogical Counselling Centre No 12, Dzielna St. 1a, 00-162 Warsaw, Poland.
Jadwiga HamulkaDepartment of Human Nutrition, Institute of Human Nutrition Sciences, Warsaw University of Life Sciences-SGGW, Nowoursynowska St. 159, 02-776 Warsaw, Poland.ORCID 0000-0003-4933-9016
Warsaw University of Life Sciences · PLLudwik Hirszfeld Institute of Immunology and Experimental Therapy · PLMedical University of Warsaw · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previous studies provided contradictory results regarding the influence of maternal, seasonal, and infant factors on breastmilk cortisol, and its associations with breastmilk composition and infant development. This study aimed to assess breastmilk cortisol levels at the first, third, and sixth months of lactation and evaluate the associations with maternal psychosocial, seasonal, and infant factors, breastmilk composition, and infant anthropometric and psychomotor development and temperament. Cortisol concentrations were assessed by ELISA in 24 h breastmilk samples obtained from 38 healthy mothers. Maternal psychological status was assessed by EPDS and PSS-10 and infant psychomotor development was assessed using the Children's Development Scale (DSR). Breastmilk cortisol was 11.2 ± 6.2, 11.2 ± 4.3, and 12.7 ± 6.2 ng/mL at the first, third, and sixth months of lactation (

Indexed as

HydrocortisoneMilk, HumanBreast FeedingChildChild DevelopmentFemaleHumansInfantLactationHydrocortisoneanthropometric developmentbody mass indexfatty acid profileglucocorticoidshuman milkmacronutrientspsychomotor developmenttemperament

Identifiers

PMID36429527
PMCPMC9690377
OpenAlexW4308873560

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.