Evidence map›Paper›PMID 36429515›Full record

ArticleInternational journal of environmental research and public health2022

Exposure to House Dust Mite Allergen and Endotoxin in Early Life and Sensitization and Allergic Rhinitis: The JECS.

Reiji Kojima, Ryoji Shinohara, Megumi Kushima, Sayaka Horiuchi, Sanae Otawa, Kunio Miyake, Hiroshi Yokomichi, Yuka Akiyama, Tadao Ooka, Zentaro Yamagata and 1 more

Abstract read
In one paragraph

Article in International journal of environmental research and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Metabolites · 2026
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Reiji KojimaDepartment of Health Sciences, School of Medicine, University of Yamanashi, Shimokato, Chuo 1110, Kofu 409-3898, Yamanashi, Japan.ORCID 0000-0002-9712-889X
Ryoji ShinoharaCenter for Birth Cohort Studies, University of Yamanashi, Shimokato, Chuo 1110, Kofu 409-3898, Yamanashi, Japan.
Megumi KushimaCenter for Birth Cohort Studies, University of Yamanashi, Shimokato, Chuo 1110, Kofu 409-3898, Yamanashi, Japan.
Sayaka HoriuchiCenter for Birth Cohort Studies, University of Yamanashi, Shimokato, Chuo 1110, Kofu 409-3898, Yamanashi, Japan.
Sanae OtawaCenter for Birth Cohort Studies, University of Yamanashi, Shimokato, Chuo 1110, Kofu 409-3898, Yamanashi, Japan.
Kunio MiyakeDepartment of Health Sciences, School of Medicine, University of Yamanashi, Shimokato, Chuo 1110, Kofu 409-3898, Yamanashi, Japan.
Hiroshi YokomichiDepartment of Health Sciences, School of Medicine, University of Yamanashi, Shimokato, Chuo 1110, Kofu 409-3898, Yamanashi, Japan.ORCID 0000-0001-7369-155X
Yuka AkiyamaDepartment of Health Sciences, School of Medicine, University of Yamanashi, Shimokato, Chuo 1110, Kofu 409-3898, Yamanashi, Japan.
Tadao OokaDepartment of Health Sciences, School of Medicine, University of Yamanashi, Shimokato, Chuo 1110, Kofu 409-3898, Yamanashi, Japan.ORCID 0000-0002-1343-3986
Zentaro YamagataDepartment of Health Sciences, School of Medicine, University of Yamanashi, Shimokato, Chuo 1110, Kofu 409-3898, Yamanashi, Japan.
The Japan Environment And Children's Study Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The association between endotoxin and allergic rhinitis (AR) is not conclusive. The aim of this study was to determine the association between endotoxin and house dust mite (HDM) allergens in dust, and HDM sensitization and AR among Japanese infants. This study included 4188 participants in the Sub-Cohort Study of the Japan Environment and Children's Study. Dust was collected from children's mattresses at age 18 months and endotoxin and HDM allergen levels were measured. A logistic regression model was used to analyze the association between endotoxin or HDM allergen and the sensitization to HDM (specific-IgE) at age 2 and AR at age 3. The median (interquartile range) endotoxin level was 375.1(186.9-826.5) EU/m

Indexed as

EndotoxinsRhinitis, AllergicAllergensAnimalsAntigens, DermatophagoidesChildChild, PreschoolCohort StudiesDustHumansInfantPyroglyphidaeAllergensAntigens, DermatophagoidesDustEndotoxinsallergic rhinitisendotoxinhouse dust mitesensitization

Identifiers

PMID36429515
PMCPMC9690251

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.