Evidence map›Paper›PMID 36429334›Full record

ArticleFoods (Basel, Switzerland)2022

Dietary Supplement of

Donghui Luo, Jiao Zeng, Jingjing Guan, Yuanyuan Xu, Rui-Bo Jia, Jin Chen, Guili Jiang, Chunxia Zhou

Open access · goldAbstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Donghui LuoSchool of Food Science and Engineering, Guangdong Ocean University, Yangjiang 529500, China.
Jiao ZengChaozhou Branch of Chemistry and Chemical Engineering Guangdong Laboratory, Chaozhou 521000, China.ORCID 0000-0001-9817-0806
Jingjing GuanSchool of Food Science and Engineering, Guangdong Ocean University, Yangjiang 529500, China.
Yuanyuan XuSchool of Food Science and Engineering, Guangdong Ocean University, Yangjiang 529500, China.
Rui-Bo JiaSchool of Food Science and Engineering, Guangdong Ocean University, Yangjiang 529500, China.
Jin ChenSchool of Food Science and Engineering, Guangdong Ocean University, Yangjiang 529500, China.
Guili JiangSchool of Food Science and Engineering, Guangdong Ocean University, Yangjiang 529500, China.
Chunxia ZhouSchool of Food Science and Engineering, Guangdong Ocean University, Yangjiang 529500, China.ORCID 0000-0001-7454-8384
Guangdong Ocean University · CNChaozhou Central Hospital · CN

Funding

Chaozhou Science and Technology Plan Project, grant number 2020PT01Key-Area Research and Development Program of Guangdong Province 2021B0707060001Self-innovation Research Funding Project of Hanjiang Laboratory HJL202104B001, HJL202101B002, HJL202101B005
6 · The paper itself

Abstract

Amomum villosum Lour. (A. villosum), a comestible medicinal plant, has been traditionally used in China to treat diarrhea, stomach fullness, and abdominal distension. Polysaccharide, the main chemical component of A. villosum, has been shown to possess potential antioxidant and glycosidase inhibitory activities; however, whether it has anticolitis activity is unknown. The aim of this research was to evaluate the anticolitis effects of A. villosum polysaccharide (AVLP) in BALB/c mice. The results showed that AVLP administration significantly reversed body weight loss, colon shortening and colon weight gain and decreased the levels of proinflammatory cytokines and chemokines in colitis mice (p < 0.05). AVLP administration also maintained intestinal barrier function by the upregulation of ZO-1 protein expression (p < 0.05). In addition, high-throughput sequencing analysis showed that AVLP possessed a great regulatory effect on the growth of Adlercreutzia, Clostridium, Streptococcus, Parabacteroides, Helicobacter, Odoribacter, and Alistipes (p < 0.05, LDA score > 2). The correlation analysis revealed that the protective effects against colitis of AVLP were highly correlated with intestinal bacterium regulation. These results suggest that AVLP intake could serve as a prospective nutritional strategy for inflammatory bowel diseases.

Indexed as

Amomum villosum Lour. polysaccharidegut floraulcerative colitis

Identifiers

PMID36429334
PMCPMC9689959
OpenAlexW4309686452

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.