Evidence map›Paper›PMID 36429262›Full record

ArticleFoods (Basel, Switzerland)2022

Zeaxanthin Dipalmitate-Enriched Emulsion Stabilized with Whey Protein Isolate-Gum Arabic Maillard Conjugate Improves Gut Microbiota and Inflammation of Colitis Mice.

Xuhui Kan, Wangting Zhou, Weiqi Xu, Zhuqing Dai, Yamei Yan, Jia Mi, Yi Sun, Xiaoxiong Zeng, Youlong Cao, Lu Lu

Open access · goldAbstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
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  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Xuhui KanCollege of Food Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.ORCID 0000-0003-1755-7537
Wangting ZhouCollege of Food Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Weiqi XuCollege of Food Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Zhuqing DaiInstitute of Agro-Product Processing, Jiangsu Academy of Agricultural Sciences, Nanjing 210014, China.
Yamei YanInstitute of Wolfberry Engineering and Technology, Ningxia Academy of Agriculture and Forestry Sciences, Yinchuan 750004, China.
Jia MiInstitute of Wolfberry Engineering and Technology, Ningxia Academy of Agriculture and Forestry Sciences, Yinchuan 750004, China.
Yi SunCollege of Food Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Xiaoxiong ZengCollege of Food Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Youlong CaoInstitute of Wolfberry Engineering and Technology, Ningxia Academy of Agriculture and Forestry Sciences, Yinchuan 750004, China.
Lu LuInstitute of Wolfberry Engineering and Technology, Ningxia Academy of Agriculture and Forestry Sciences, Yinchuan 750004, China.
Nanjing Agricultural University · CNNingxia Academy of Agriculture and Forestry Sciences · CNJiangsu Academy of Agricultural Sciences · CN

Funding

Independent Innovation Fund Project of Agricultural Science and Technology in Jiangsu Province CX(20)3045Key Research and Development Project funded by Ningxia Hui Autonomous Region of China 2021BEF02008National Natural Science Foundation of China 31801541, 31860083Postgraduate Research & Practice Innovation Program of Jiangsu Province KYCX22_0721Priority Academic Program Development of Jiangsu Higher Education Institutions PAPD
6 · The paper itself

Abstract

In the present study, protein-polysaccharide Maillard conjugates were used as novel emulsifiers and bioactive carriers. Effects and potential mechanisms of zeaxanthin dipalmitate (ZD)-enriched emulsion stabilized with whey protein isolate (WPI)-gum Arabic (GA) conjugate (WPI-GA-ZD) and ZD-free emulsion (WPI-GA) on gut microbiota and inflammation were investigated using a model of dextran sulfate sodium (DSS)-induced colitis in mice. As a result, supplementation with WPI-GA and WPI-GA-ZD improved the serum physiological and biochemical indicators, decreased the expression of pro-inflammatory cytokines and related mRNA, as well as increased the tight junction proteins to a certain extent. 16S rDNA sequencing analyses showed that supplementation with WPI-GA and WPI-GA-ZD presented differential modulation of gut microbiota and played regulatory roles in different metabolic pathways to promote health. Compared with WPI-GA, the relative abundances of

Indexed as

colitisgut microbiotaLycium barbarumprotein-polysaccharide conjugatezeaxanthin dipalmitate

Identifiers

PMID36429262
PMCPMC9689712
OpenAlexW4309607978

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.