Evidence map›Paper›PMID 36429137›Full record

ArticleFoods (Basel, Switzerland)2022

Effect of a Novel Sugar Blend on Weight and Cardiometabolic Health among Healthy Indian Adults: A Randomized, Open-Label Study.

Srinath Aswathiah, Sunil Kumar Prabhu, Ramanna Lingaiah, Anusha Ramanna, Jyothi S Prabhu, Shashi Kishor Pankaj, Arti Mehta, Arohi Bapna, Govindarajan Raghavan

Abstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Srinath AswathiahBGS Gleneagles Global Hospitals, Bangalore 560060, India.
Sunil Kumar PrabhuSarani Bio-Integra Private Limited, Bangalore 560062, India.
Ramanna LingaiahTirumala Healthcare Limited, Bangalore 560085, India.
Anusha RamannaTirumala Healthcare Limited, Bangalore 560085, India.
Jyothi S PrabhuSt. Johns Research Institute, Bangalore 560034, India.
Shashi Kishor PankajZydus Wellness R&D Centre, Zydus Wellness Institute, S.G. Highway, Off Ambli-Bopal Road, Ahmedabad 380058, India.
Arti MehtaZydus Wellness R&D Centre, Zydus Wellness Institute, S.G. Highway, Off Ambli-Bopal Road, Ahmedabad 380058, India.
Arohi BapnaZydus Wellness R&D Centre, Zydus Wellness Institute, S.G. Highway, Off Ambli-Bopal Road, Ahmedabad 380058, India.
Govindarajan RaghavanZydus Wellness R&D Centre, Zydus Wellness Institute, S.G. Highway, Off Ambli-Bopal Road, Ahmedabad 380058, India.ORCID 0000-0001-9093-1287

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Obesity is one of the major factors contributing to noncommunicable diseases (NCDs), which is associated with a high intake of a sugar-rich diet. Sugar blend (a novel combination of sugar and stevia) has half the calories of sugar with the same sweetness at recommended use and offers better compliance. A randomized controlled trial was conducted to evaluate the efficacy and safety of this sugar blend in normal to mildly overweight subjects with a body mass index (BMI) of 23−26 kg/m. Sixty subjects were categorized into Group A: Sugar group (n = 30), and Group B: Sugar blend group (n = 30). The primary outcomes evaluated were weight, waist circumference, hip circumference, waist/hip ratio, BMI, and the secondary outcomes evaluated were lipid profile, random blood sugar, and HbA1c. All these parameters were assessed at baseline, 30 days, 60 days, and 90 days. Group B showed a significantly higher weight loss (p = 0.013) at 90 days compared with Group A. A significant reduction in waist circumference (p < 0.0001) by 4.4 cm was noted at 90 days, in addition to reduction in total cholesterol (p < 0.0001), triglyceride (p = 0.006), LDL cholesterol (p = 0.0490), and VLDL cholesterol (p = 0.006) in Group B compared with the baseline. The study revealed that the sugar blend is an effective formulation in reducing weight, anthropometric factors, and other related metabolic parameters. It has been proven to be well tolerated and promotes weight loss when used in conjunction with a daily balanced diet and exercise plan.

Indexed as

body mass index (BMI)noncommunicable diseases (NCDs)obesitysteviasteviol glycosides (SGs)weight loss

Identifiers

PMID36429137
PMCPMC9689513

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.