Evidence map›Paper›PMID 36429125›Full record

ReviewCells2022

Etiopathogenesis, Diagnosis, and Treatment Strategies for Lymphomatoid Papulosis with Particular Emphasis on the Role of the Immune System.

Danuta Nowicka, Paulina Mertowska, Sebastian Mertowski, Anna Hymos, Alicja Forma, Adam Michalski, Izabela Morawska, Rafał Hrynkiewicz, Paulina Niedźwiedzka-Rystwej, Ewelina Grywalska

Abstract readReview
In one paragraph

Review in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Danuta NowickaDepartment of Dermatology, Venereology and Allergology, Wrocław Medical University, 50-368 Wrocław, Poland.ORCID 0000-0002-1717-4280
Paulina MertowskaDepartment of Experimental Immunology, Medical University of Lublin, 20-093 Lublin, Poland.ORCID 0000-0001-9530-6659
Sebastian MertowskiDepartment of Experimental Immunology, Medical University of Lublin, 20-093 Lublin, Poland.ORCID 0000-0002-7121-1396
Anna HymosDepartment of Experimental Immunology, Medical University of Lublin, 20-093 Lublin, Poland.
Alicja FormaDepartment of Forensic Medicine, Medical University of Lublin, 20-090 Lublin, Poland.ORCID 0000-0001-8714-7627
Adam MichalskiDepartment of Clinical Immunology and Immunotherapy, Medical University of Lublin, 20-093 Lublin, Poland.ORCID 0000-0001-9598-373X
Izabela MorawskaDepartment of Clinical Immunology and Immunotherapy, Medical University of Lublin, 20-093 Lublin, Poland.ORCID 0000-0001-9462-8779
Rafał HrynkiewiczInstitute of Biology, University of Szczecin, 71-412 Szczecin, Poland.ORCID 0000-0002-0688-6928
Paulina Niedźwiedzka-RystwejInstitute of Biology, University of Szczecin, 71-412 Szczecin, Poland.ORCID 0000-0003-4065-3842
Ewelina GrywalskaDepartment of Experimental Immunology, Medical University of Lublin, 20-093 Lublin, Poland.ORCID 0000-0002-0451-4741

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lymphomatoid papulosis (LyP) is a very rare disease that belongs to the group of CD30+ lymphoproliferative skin diseases. LyP is localized or generalized and usually presents as isolated or clustered red/brown-red lesions in the form of nodules and/or papules. The course of the disease is in most cases mild; however, depending on concomitant risk factors and history, it may progress to lymphoma, significantly reducing the survival rate and prognosis. Importantly, the clinical picture of the disease remains somewhat ambiguous, leading to a large number of misdiagnoses that result in inappropriate treatment, which is usually insufficient to alleviate symptoms. In addition to clinical manifestations, the histological characteristics vary widely and usually overlap with other conditions, especially those belonging to the group of lymphoproliferative disorders. Although diagnosis remains a challenge, several recommendations and guidelines have been introduced to standardize and facilitate the diagnostic process. This article reviews the available literature on the most important aspects of etiopathogenesis, clinical and histopathological features, diagnostic criteria, and possible treatment strategies for LyP, with particular emphasis on the role of the immune system.

Indexed as

Lymphomatoid PapulosisSkin DiseasesDiagnostic ErrorsHumansHyperplasiaImmune SystemCD30dermatologydiagnosishistopathologyimmune systemimmunophenotypinglymphoproliferative disordertreatment

Identifiers

PMID36429125
PMCPMC9688547

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.