Evidence map›Paper›PMID 36429119›Full record

ArticleCells2022

Inactivation of Autophagy in Keratinocytes Reduces Tumor Growth in Mouse Models of Epithelial Skin Cancer.

Caterina Barresi, Heidemarie Rossiter, Maria Buchberger, Johannes Pammer, Supawadee Sukseree, Maria Sibilia, Erwin Tschachler, Leopold Eckhart

Open access · goldAbstract read
In one paragraph

Article in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Caterina BarresiDepartment of Dermatology, Medical University of Vienna, 1090 Vienna, Austria.
Heidemarie RossiterDepartment of Dermatology, Medical University of Vienna, 1090 Vienna, Austria.
Maria BuchbergerDepartment of Dermatology, Medical University of Vienna, 1090 Vienna, Austria.
Johannes PammerClinical Institute of Pathology, Medical University of Vienna, 1090 Vienna, Austria.
Supawadee SuksereeDepartment of Dermatology, Medical University of Vienna, 1090 Vienna, Austria.
Maria SibiliaCenter for Cancer Research, Comprehensive Cancer Center, Medical University of Vienna, 1090 Vienna, Austria.
Erwin TschachlerDepartment of Dermatology, Medical University of Vienna, 1090 Vienna, Austria.
Leopold EckhartDepartment of Dermatology, Medical University of Vienna, 1090 Vienna, Austria.ORCID 0000-0002-5645-2036
Medical University of Vienna · ATComprehensive Cancer Center Vienna · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autophagy is a ubiquitous degradation mechanism, which plays a critical role in cellular homeostasis. To test whether autophagy suppresses or supports the growth of tumors in the epidermis of the skin, we inactivated the essential autophagy gene

Indexed as

Neoplasms, Glandular and EpithelialSkin NeoplasmsAnimalsAutophagyCell Transformation, NeoplasticDisease Models, AnimalErbB ReceptorsKeratinocytesMiceErbB Receptorsautophagycarcinogenesisepidermal growth factorepidermisepitheliumkeratinocytessquamous cell carcinomatumor

Identifiers

PMID36429119
PMCPMC9688105
OpenAlexW4309785965

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.