Evidence map›Paper›PMID 36429105›Full record

ArticleCells2022

Clinical Significance of Diabetes-Mellitus-Associated Antibodies in Rheumatoid Arthritis.

Malin C Erlandsson, Mahomud Tuameh, Elin Jukic Huduti, Sofia T Silfverswärd, Rille Pullerits, Maria I Bokarewa

Open access · goldAbstract read
In one paragraph

Article in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Malin C ErlandssonDepartment of Rheumatology and Inflammation Research, Institute of Medicine, The Sahlgrenska Academy at University of Gothenburg, Guldhedsgatan 10A, SE-41345 Gothenburg, Sweden.ORCID 0000-0003-1100-7577
Mahomud TuamehDepartment of Rheumatology and Inflammation Research, Institute of Medicine, The Sahlgrenska Academy at University of Gothenburg, Guldhedsgatan 10A, SE-41345 Gothenburg, Sweden.ORCID 0000-0002-5496-3932
Elin Jukic HudutiDepartment of Rheumatology and Inflammation Research, Institute of Medicine, The Sahlgrenska Academy at University of Gothenburg, Guldhedsgatan 10A, SE-41345 Gothenburg, Sweden.
Sofia T SilfverswärdDepartment of Rheumatology and Inflammation Research, Institute of Medicine, The Sahlgrenska Academy at University of Gothenburg, Guldhedsgatan 10A, SE-41345 Gothenburg, Sweden.
Rille PulleritsDepartment of Rheumatology and Inflammation Research, Institute of Medicine, The Sahlgrenska Academy at University of Gothenburg, Guldhedsgatan 10A, SE-41345 Gothenburg, Sweden.ORCID 0000-0002-5383-9817
Maria I BokarewaDepartment of Rheumatology and Inflammation Research, Institute of Medicine, The Sahlgrenska Academy at University of Gothenburg, Guldhedsgatan 10A, SE-41345 Gothenburg, Sweden.ORCID 0000-0001-9424-5145
Sahlgrenska University Hospital · SEUniversity of Gothenburg · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rheumatoid arthritis (RA) is a canonical autoimmune disease that shares numerous risk factors with diabetes mellitus (DM). The production of autoantibodies is a characteristic feature in both diseases. To determine the frequency and specificity of DM-related antibodies (DMab) in RA patients and to study whether DMab associates with new DM cases in RA patients, we measured DMab defined as IgG against glutamic acid decarboxylase (GADA), tyrosine phosphatase (IA2-ab), and zinc transporter (ZnT8-ab) in a cohort of 290 RA patients (215 women and 75 men, median disease duration 11 years). Of those, 21 had a DM diagnosis at baseline. The development of new DM cases and mortality were traced in a 10-year prospective follow-up. Predictive analyses for DM and mortality were carried out by the Mantel-Cox regression. We found that 27 of the patients (9.3%) had DMab, equally often men and women. The presence of DMab was more frequent in patients with DM (

Indexed as

Arthritis, RheumatoidAutoimmune DiseasesDiabetes MellitusAutoantibodiesFemaleHumansMaleProspective StudiesAutoantibodiesautoantibodiesdiabetes mellitusprospective follow-uprheumatoid arthritis

Identifiers

PMID36429105
PMCPMC9688717
OpenAlexW4309683168

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.