Evidence map›Paper›PMID 36428998›Full record

ArticleCells2022

Evaluation of the Hematological and Serum Biochemistry Parameters in the Pre-Symptomatic and Symptomatic Stages of ALS Disease to Support Early Diagnosis and Prognosis.

Duygu Aydemir, Selcuk Surucu, Ayse Nazli Basak, Nuriye Nuray Ulusu

Abstract read
In one paragraph

Article in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Duygu AydemirDepartment of Medical Biochemistry, School of Medicine, Koc University, Sariyer, Istanbul 34450, Turkey.ORCID 0000-0002-6449-2708
Selcuk SurucuDepartment of Anatomy, School of Medicine, Koc University, Sariyer, Istanbul 34450, Turkey.
Ayse Nazli BasakSuna and İnan Kıraç Foundation, Neurodegeneration Research Laboratory, NDAL-KUTTAM, School of Medicine, Koç University, Istanbul 34010, Turkey.ORCID 0000-0001-6977-2517
Nuriye Nuray UlusuDepartment of Medical Biochemistry, School of Medicine, Koc University, Sariyer, Istanbul 34450, Turkey.ORCID 0000-0002-3173-1389

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Amyotrophic lateral sclerosis (ALS) is the most common motor neuron disease. Since there are no pathognomonic tests for ALS prognoses; clinical diagnoses of the disease take time and are usually difficult. Prognostic biomarkers are urgently needed for rapid and effective ALS prognoses. Male albino rats were divided into ten groups based on age: 0 (40-45 days old), A (70-75 days old), B (90-95 days old), C (110-115 days old), and D (130-135 days old). Each group was divided into two subgroups according to its mutation status: wild type (SOD1

Indexed as

Amyotrophic Lateral SclerosisAnimalsBiomarkersDisease Models, AnimalEarly DiagnosisMaleQuality of LifeRatsSuperoxide DismutaseSuperoxide Dismutase-1BiomarkersSuperoxide DismutaseSuperoxide Dismutase-1ALSearly diagnosishematological parameterspre-symptomaticserum biochemistrysymptomatic

Identifiers

PMID36428998
PMCPMC9688239

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.