Evidence map›Paper›PMID 36428859›Full record

ReviewDiagnostics (Basel, Switzerland)2022

Exploring the Mechanisms and Association between Oral Microflora and Systemic Diseases.

Rakhi Issrani, Jagat Reddy, Tarek H El-Metwally Dabah, Namdeo Prabhu, Mohammed Katib Alruwaili, Manay Srinivas Munisekhar, Sultan Meteb Alshammari, Shmoukh Fahad Alghumaiz

Open access · goldAbstract readReview
In one paragraph

Review in Diagnostics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

  1. Multidrug-resistant Pseudomonas aeruginosa in ICU patients and hospital surfaces: β-lactamase burden, biofilm formation and clonal spread.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  2. Review
  3. Article
  4. Article
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  6. Advancing oral immunology for improving oral health.Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie · 2025
    Review
  7. Article
  8. Review
  9. Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 4 countries.

Rakhi IssraniDepartment of Preventive Dentistry, College of Dentistry, Jouf University, Sakaka 72388, Saudi Arabia.ORCID 0000-0002-0046-3529
Jagat ReddyOral Medicine & Radiology, Indira Gandhi Institute of Dental Sciences, SBV University, Puducherry 607402, India.
Tarek H El-Metwally DabahDepartment of Preventive Dentistry, College of Dentistry, Jouf University, Sakaka 72388, Saudi Arabia.ORCID 0000-0001-9040-6642
Namdeo PrabhuDepartment of Oral & Maxillofacial Surgery and Diagnostic Sciences, College of Dentistry, Jouf University, Sakaka 72388, Saudi Arabia.
Mohammed Katib AlruwailiDepartment of Preventive Dentistry, College of Dentistry, Jouf University, Sakaka 72388, Saudi Arabia.ORCID 0000-0001-6677-8745
Manay Srinivas MunisekharDepartment of Preventive Dentistry, College of Dentistry, Jouf University, Sakaka 72388, Saudi Arabia.
Sultan Meteb AlshammariDepartment of Oral & Maxillofacial Surgery and Diagnostic Sciences, College of Dentistry, Jouf University, Sakaka 72388, Saudi Arabia.ORCID 0000-0001-8503-4725
Shmoukh Fahad AlghumaizDepartment of Oral & Maxillofacial Surgery and Diagnostic Sciences, College of Dentistry, Jouf University, Sakaka 72388, Saudi Arabia.
Jouf University · SASri Balaji Vidyapeeth University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The scope of dentistry is ever-changing and dynamic in all fields of dentistry including periodontal health and disease. Recent studies show that oral health and systemic health are interdependent, particularly in the way that poor oral hygiene and periodontal health affect the systemic health of an individual and vice versa. Periodontal diseases are multifactorial in nature in which the role of bacterial infections is inevitable. Furthermore, high-throughput sequencing technologies have shed light on the dysregulation of the growth of oral microbial flora and their environment, including those that are associated with periodontitis and other oral and non-oral diseases. Under such circumstances, it becomes important to explore oral microbiota and understand the effects of periodontal pathogens in the pathogenesis of systemic diseases. In addition, it may strengthen our view that a better understanding of oral microbial flora and proper examination of the oral cavity may aid in the early diagnosis and possible treatment of systemic diseases and conditions. This will eventually lead to providing better care to our patients. Therefore, in this research, we attempt to outline the periodontal pathophysiology along with the role of periodontal pathogens in some commonly encountered systemic conditions.

Indexed as

bacteriadiseasespathogensperiodontitissystemic

Identifiers

PMID36428859
PMCPMC9689323
OpenAlexW4309316677

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.