Evidence map›Paper›PMID 36428856›Full record

ArticleDiagnostics (Basel, Switzerland)2022

Sex and Age Influence on Association of

Carmen Flores-Pérez, Janett Flores-Pérez, Manuel de Jesús Castillejos López, Juan Luis Chávez-Pacheco, Karla Miroslava Tejada-Gutiérrez, Arnoldo Aquino-Gálvez, Luz María Torres-Espíndola

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Carmen Flores-PérezLaboratory of Pharmacology, National Institute of Pediatrics (INP), Mexico City 04530, Mexico.
Janett Flores-PérezLaboratory of Pharmacology, National Institute of Pediatrics (INP), Mexico City 04530, Mexico.
Manuel de Jesús Castillejos LópezEpidemiological Surveillance Unit, National Institute of Respiratory Diseases, Mexico City 14080, Mexico.ORCID 0000-0001-8689-9755
Juan Luis Chávez-PachecoLaboratory of Pharmacology, National Institute of Pediatrics (INP), Mexico City 04530, Mexico.ORCID 0000-0001-6919-4497
Karla Miroslava Tejada-GutiérrezLaboratory of Pharmacology, National Institute of Pediatrics (INP), Mexico City 04530, Mexico.
Arnoldo Aquino-GálvezMolecular Biology Laboratory, National Institute of Respiratory Diseases, Mexico City 14080, Mexico.ORCID 0000-0002-2869-5516
Luz María Torres-EspíndolaLaboratory of Pharmacology, National Institute of Pediatrics (INP), Mexico City 04530, Mexico.
Universidad Autónoma Metropolitana · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Midazolam is a drug that is metabolized by cytochrome P450 (CYP450) enzymes, particularly CYP3A4 and CYP3A5. The present study aimed to determine the sex and age influence on association of CYP450 polymorphism with midazolam levels in critically ill children. Seventy-two DNA samples were genotyped by real-time PCR. Children ≤ five years of age who carry the rs776746 (T) allele in

Indexed as

critically illcytochrome P-450 CYP3Amidazolampediatricspharmacokineticssex

Identifiers

PMID36428856
PMCPMC9689687
OpenAlexW4309152644

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.