Evidence map›Paper›PMID 36428822›Full record

ArticleDiagnostics (Basel, Switzerland)2022

Identification of Uric Acid Crystals Accumulation in Human and Animal Tissues Using Combined Morphological and Raman Spectroscopy Analysis.

Teodoru Soare, Ana Maria Iordache, George Nicolae, Stefan-Marian Iordache, Cosmin Baciu, Silviu Marinescu, Raluca Ioana Rizac, Manuella Militaru

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.1field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Teodoru SoareDepartment of Pathology, Faculty of Veterinary Medicine, University of Agronomic Sciences and Veterinary Medicine of Bucharest, Splaiul Independentei Street, No. 105, Sector 5, 050097 Bucharest, Romania.
Ana Maria IordacheOptospintronics Department, National Institute for Research and Development for Optoelectronics-INOE 2000, 077125 Magurele, Romania.ORCID 0000-0003-4705-0606
George NicolaeDepartment of Pathology, Faculty of Veterinary Medicine, University of Agronomic Sciences and Veterinary Medicine of Bucharest, Splaiul Independentei Street, No. 105, Sector 5, 050097 Bucharest, Romania.
Stefan-Marian IordacheOptospintronics Department, National Institute for Research and Development for Optoelectronics-INOE 2000, 077125 Magurele, Romania.ORCID 0000-0002-9840-9896
Cosmin BaciuDepartment 14 Orthopedy-Traumatology-ATI, University of Medicine and Pharmacy Carol Davilla (UMFCD), Dionisie Lupu Street, No. 37, Sector 2, 020021 Bucharest, Romania.ORCID 0000-0002-7800-9190
Silviu MarinescuDepartment 11-Plastic and Reconstructive Surgery, Pediatric Surgery, University of Medicine and Pharmacy Carol Davilla (UMFCD), Eroii Sanitari Bvd., No. 8, Sector 5, 050471 Bucharest, Romania.
Raluca Ioana RizacDepartment of Pathology, Faculty of Veterinary Medicine, University of Agronomic Sciences and Veterinary Medicine of Bucharest, Splaiul Independentei Street, No. 105, Sector 5, 050097 Bucharest, Romania.ORCID 0000-0001-9566-6216
Manuella MilitaruDepartment of Pathology, Faculty of Veterinary Medicine, University of Agronomic Sciences and Veterinary Medicine of Bucharest, Splaiul Independentei Street, No. 105, Sector 5, 050097 Bucharest, Romania.
University of Agronomic Sciences and Veterinary Medicine of Bucharest · ROCarol Davila University of Medicine and Pharmacy · RONational Institute of Research and Development for Optoelectronics · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gout is a metabolic condition, common to animals and humans, issuing from the excessive accumulation of end products of proteins degradation. In this study, histopathological and cytological examinations, combined with Raman spectroscopy, have been performed to investigate tissue samples from reptiles, chickens, and humans, presenting lesions produced by uric acid accumulation. As a result of classic processing and staining techniques commonly used in the anatomopathological diagnosis, uric acid crystals lose their structural characteristics, thus making difficult a precise diagnostic. Therefore, complementary diagnostic methods, such as Raman spectroscopy, are needed. This study compares from several perspectives the above mentioned diagnostic methods, concluding that Raman spectroscopy provides highlights in the diagnosis of gout in humans and animals, also adding useful information to differential diagnosis of lesions.

Indexed as

comparative pathologycrystalsgouthumanpoultryRaman spectroscopyreptilesuric acid

Identifiers

PMID36428822
PMCPMC9689726
OpenAlexW4309307007

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.