Evidence map›Paper›PMID 36428694›Full record

ArticleCancers2022

Trabectedin Is Active against Two Novel, Patient-Derived Solitary Fibrous Pleural Tumor Cell Lines and Synergizes with Ponatinib.

Bahil Ghanim, Dina Baier, Christine Pirker, Leonhard Müllauer, Katharina Sinn, Gyoergy Lang, Konrad Hoetzenecker, Walter Berger

Abstract read
In one paragraph

Article in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Systemic Therapy for Solitary Fibrous Tumor.Current treatment options in oncology · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Bahil GhanimDepartment of Thoracic Surgery, Medical University of Vienna, 1090 Vienna, Austria.ORCID 0000-0002-6563-5643
Dina BaierCenter for Cancer Research and Comprehensive Cancer Center, Medical University of Vienna, 1090 Vienna, Austria.ORCID 0000-0002-4328-7035
Christine PirkerCenter for Cancer Research and Comprehensive Cancer Center, Medical University of Vienna, 1090 Vienna, Austria.
Leonhard MüllauerDepartment of Pathology, Medical University of Vienna, 1090 Vienna, Austria.ORCID 0000-0002-3399-078X
Katharina SinnDepartment of Thoracic Surgery, Medical University of Vienna, 1090 Vienna, Austria.ORCID 0000-0002-3936-2354
Gyoergy LangDepartment of Thoracic Surgery, Medical University of Vienna, 1090 Vienna, Austria.ORCID 0000-0002-8839-6649
Konrad HoetzeneckerDepartment of Thoracic Surgery, Medical University of Vienna, 1090 Vienna, Austria.
Walter BergerCenter for Cancer Research and Comprehensive Cancer Center, Medical University of Vienna, 1090 Vienna, Austria.ORCID 0000-0003-0014-1658

Funding

Margaretha Hehberger Stiftung 15129
6 · The paper itself

Abstract

Solitary fibrous tumor of the pleura (SFT) is a rare disease. Besides surgery combined with radiotherapy in nondisseminated stages, curative options are currently absent. Out of fourteen primo-cell cultures, established from surgical SFT specimens, two showed stable in vitro growth. Both cell models harbored the characteristic

Indexed as

dasatinibin vitroNAB2-STAT6 gene fusionpatient-derived cell linesponatinibsolitary fibrous tumortargeted therapytrabectedin

Identifiers

PMID36428694
PMCPMC9688590

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.