Evidence map›Paper›PMID 36428596›Full record

ArticleCancers2022

Restoration of CD4

Madison Isbell, Faridoddin Mirshahi, Hussein F Aqbi, Chunqing Guo, Mulugeta Saneshaw, Nicholas Koelsch, Michael O Idowu, Dana Austin, Cohava Gelber, Xiang-Yang Wang and 2 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Madison IsbellDepartment of Microbiology & Immunology, VCU School of Medicine, Richmond, VA 23298, USA.
Faridoddin MirshahiDepartment of Internal Medicine, VCU School of Medicine, Richmond, VA 23298, USA.
Hussein F AqbiDepartment of Microbiology & Immunology, VCU School of Medicine, Richmond, VA 23298, USA.
Chunqing GuoVCU Massey Cancer Center, 401 College Street, Richmond, VA 23298, USA.
Mulugeta SaneshawDepartment of Internal Medicine, VCU School of Medicine, Richmond, VA 23298, USA.
Nicholas KoelschDepartment of Microbiology & Immunology, VCU School of Medicine, Richmond, VA 23298, USA.ORCID 0000-0002-6332-0007
Michael O IdowuVCU Massey Cancer Center, 401 College Street, Richmond, VA 23298, USA.
Dana AustinSerpin Pharma, 9501 Discovery Blvd., Suite 120, Manassas, VA 20109, USA.
Cohava GelberSerpin Pharma, 9501 Discovery Blvd., Suite 120, Manassas, VA 20109, USA.
Xiang-Yang WangVCU Massey Cancer Center, 401 College Street, Richmond, VA 23298, USA.
Arun J SanyalVCU Massey Cancer Center, 401 College Street, Richmond, VA 23298, USA.
Masoud H ManjiliDepartment of Microbiology & Immunology, VCU School of Medicine, Richmond, VA 23298, USA.ORCID 0000-0001-7511-2953
Virginia Cancer Institute · USChildren's Hospital of Richmond at VCU · USSerpin Pharma (United States) · USMustansiriyah University · IQ

Funding

Virus Vector Shared ResourceP30CA016059 · NCI · VIRGINIA COMMONWEALTH UNIVERSITY · PI Renato Martins · 1985 to 2026
$51.0M
Metabolic reprograming of fatty acid beta-oxidation to improve cancer immunotherapyR01CA229812 · NCI · VIRGINIA COMMONWEALTH UNIVERSITY · PI FANG, XIANJUN, WANG, XIANG-YANG SHAWN · 2019 to 2023
$2.0M
Innate Pattern Recognition Receptor and Acetaminophen-induced Liver InjuryI01BX003275 · VA · VA VETERANS ADMINISTRATION HOSPITAL · PI Xiang-Yang Shawn Wang · 2019 to 2026
–
BLRD VA I01 BX003275National Institute of Health R01DK105961NCI NIH HHS P30 CA016059NCI NIH HHS R01 CA229812VA 1I01BX003275
6 · The paper itself

Abstract

Predominant inflammatory immunological patterns as well as the depletion of CD4

Indexed as

hepatocellular carcinomaimmunological patterninflammationNAFLDtumor microenvironment

Identifiers

PMID36428596
PMCPMC9688124
OpenAlexW4308712559

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.