Evidence map›Paper›PMID 36428515›Full record

ArticleBiomedicines2022

Alteration of Gut Immunity and Microbiome in Mixed Granulocytic Asthma.

Bon-Hee Gu, Chae-Yun Rim, Sangjin Lee, Tae-Yong Kim, Sang-Seok Joo, Sang-Jin Lee, Han-Ki Park, Myunghoo Kim

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
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  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Bon-Hee GuLife and Industry Convergence Research Institute, Pusan National University, Miryang 50463, Republic of Korea.
Chae-Yun RimDepartment of Animal Science, College of Natural Resources & Life Science, Pusan National University, Miryang 50463, Republic of Korea.ORCID 0000-0001-6568-0383
Sangjin LeeDepartment of Animal Science, College of Natural Resources & Life Science, Pusan National University, Miryang 50463, Republic of Korea.ORCID 0000-0002-0942-6564
Tae-Yong KimDepartment of Animal Science, College of Natural Resources & Life Science, Pusan National University, Miryang 50463, Republic of Korea.
Sang-Seok JooDepartment of Animal Science, College of Natural Resources & Life Science, Pusan National University, Miryang 50463, Republic of Korea.
Sang-Jin LeeDepartment of Internal Medicine, School of Medicine, Kyungpook National University, Daegu 41944, Republic of Korea.
Han-Ki ParkDivision of Allergy and Clinical Immunology, Department of Internal Medicine, School of Medicine, Kyungpook National University, Kyungpook National University Chilgok Hospital, Daegu 41404, Republic of Korea.
Myunghoo KimLife and Industry Convergence Research Institute, Pusan National University, Miryang 50463, Republic of Korea.
Pusan National University · KRKyungpook National University · KRKyungpook National University Hospital · KR

Funding

Pusan National University PNU-RENovation (2021-2022)
6 · The paper itself

Abstract

Growing evidence suggests that there is an essential link between the gut and lungs. Asthma is a common chronic inflammatory disease and is considered a heterogeneous disease. While it has been documented that eosinophilic asthma affects gut immunity and the microbiome, the effect of other types of asthma on the gut environment has not been examined. In this study, we utilized an OVA/poly I:C-induced mixed granulocytic asthma model and found increased Tregs without significant changes in other inflammatory cells in the colon. Interestingly, an altered gut microbiome has been observed in a mixed granulocytic asthma model. We observed an increase in the relative abundance of

Indexed as

gut microbiotaintestinal immune cellsmicrobial metabolismmixed granulocytic asthma

Identifiers

PMID36428515
PMCPMC9687559
OpenAlexW4309603734

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.