Evidence map›Paper›PMID 36428502›Full record

ReviewBiomedicines2022

Rodent Models of Audiogenic Epilepsy: Genetic Aspects, Advantages, Current Problems and Perspectives.

David G Garbuz, Artem A Davletshin, Svetlana A Litvinova, Irina B Fedotova, Natalya M Surina, Inga I Poletaeva

Open access · goldAbstract readReview
In one paragraph

Review in Biomedicines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Ontogeny of the Epileptic System in the Krushinsky-Molodkina Rat Strain with Genetically Determined Audiogenic Epilepsy.Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections · 2025
    Article
  3. Rat Models in Post-Traumatic Stress Disorder Research: Strengths, Limitations, and Implications for Translational Studies.Pathophysiology : the official journal of the International Society for Pathophysiology · 2024
    Review
  4. Article
  5. International journal of molecular sciences · 2023
    Article
  6. Review
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

David G GarbuzLaboratory of Molecular Mechanisms of Biological Adaptation, Engelhardt Institute of Molecular Biology of the Russian Academy of Sciences, 119991 Moscow, Russia.
Artem A DavletshinLaboratory of Molecular Mechanisms of Biological Adaptation, Engelhardt Institute of Molecular Biology of the Russian Academy of Sciences, 119991 Moscow, Russia.ORCID 0000-0002-2635-9279
Svetlana A LitvinovaLaboratory of Psychopharmacology of FSBI "Zakusov Institute of Pharmacology", 125315 Moscow, Russia.
Irina B FedotovaChair of Higher Nervous Activity, Biology Department, Lomonosov Moscow State University, 119991 Moscow, Russia.
Natalya M SurinaChair of Higher Nervous Activity, Biology Department, Lomonosov Moscow State University, 119991 Moscow, Russia.
Inga I PoletaevaChair of Higher Nervous Activity, Biology Department, Lomonosov Moscow State University, 119991 Moscow, Russia.ORCID 0000-0002-1277-9918
Lomonosov Moscow State University · RUEngelhardt Institute of Molecular Biology · RUInstitute of Pharmacology Russian Academy of Medical Sciences · RU

Funding

Russian Science Foundation 19-14-00167
6 · The paper itself

Abstract

Animal models of epilepsy are of great importance in epileptology. They are used to study the mechanisms of epileptogenesis, and search for new genes and regulatory pathways involved in the development of epilepsy as well as screening new antiepileptic drugs. Today, many methods of modeling epilepsy in animals are used, including electroconvulsive, pharmacological in intact animals, and genetic, with the predisposition for spontaneous or refractory epileptic seizures. Due to the simplicity of manipulation and universality, genetic models of audiogenic epilepsy in rodents stand out among this diversity. We tried to combine data on the genetics of audiogenic epilepsy in rodents, the relevance of various models of audiogenic epilepsy to certain epileptic syndromes in humans, and the advantages of using of rodent strains predisposed to audiogenic epilepsy in current epileptology.

Indexed as

audiogenic epilepsyepilepsy-associated genesepileptogenesisGASH/Sal hamster straingenetic epilepsy modelsKM ratsWAR rats

Identifiers

PMID36428502
PMCPMC9687921
OpenAlexW4309307118

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.