Evidence map›Paper›PMID 36428495›Full record

ArticleBiomedicines2022

Angiotensin II Modulates Calcium/Phosphate Excretion in Experimental Model of Hypertension: Focus on Bone.

Giovanna Castoldi, Raffaella Carletti, Silvia Ippolito, Isabella Villa, Biagio Palmisano, Simona Bolamperti, Alessandro Rubinacci, Gianpaolo Zerbini, Michela Meani, Giovanni Zatti and 1 more

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Giovanna CastoldiDipartimento di Medicina e Chirurgia, Università degli Studi di Milano-Bicocca, 20900 Monza, Italy.
Raffaella CarlettiDipartimento di Medicina Traslazionale e di Precisione, Sapienza Università di Roma, 00185 Rome, Italy.
Silvia IppolitoLaboratorio Analisi Chimico Cliniche, Ospedale San Gerardo, ASST Monza, 20900 Monza, Italy.
Isabella VillaLaboratorio di Endocrinologia e Metabolismo Osseo, Istituto di Endocrinologia e Scienze Metaboliche, IRCCS Ospedale San Raffaele, 20132 Milano, Italy.ORCID 0000-0002-3732-4725
Biagio PalmisanoDipartimento di Medicina Molecolare, Sapienza Università di Roma, 00161 Roma, Italy.ORCID 0000-0002-1287-5256
Simona BolampertiLaboratorio di Endocrinologia e Metabolismo Osseo, Istituto di Endocrinologia e Scienze Metaboliche, IRCCS Ospedale San Raffaele, 20132 Milano, Italy.ORCID 0000-0002-8940-8859
Alessandro RubinacciOsteoporosis and Bone and Mineral Metabolism Unit, IRCCS Ospedale San Raffaele, 20132 Milano, Italy.ORCID 0000-0003-1736-0531
Gianpaolo ZerbiniUnita' Complicanze del Diabete, IRCCS Ospedale San Raffaele, 20132 Milano, Italy.ORCID 0000-0001-6181-089X
Michela MeaniDipartimento di Medicina e Chirurgia, Università degli Studi di Milano-Bicocca, 20900 Monza, Italy.
Giovanni ZattiDipartimento di Medicina e Chirurgia, Università degli Studi di Milano-Bicocca, 20900 Monza, Italy.
Cira R T di GioiaDipartimento di Scienze Radiologiche, Oncologiche e Anatomopatologiche, Istituto di Anatomia Patologica, Sapienza Università di Roma, 00161 Rome, Italy.ORCID 0000-0003-4696-0560
IRCCS Ospedale San Raffaele · ITAzienda Ospedaliera San Gerardo · ITSapienza University of Rome · ITUniversity of Milano-Bicocca · IT

Funding

Universita' Milano Bicocca. Fondo Ateneo Ricerca (G.Za) FAR G.Za 2020
6 · The paper itself

Abstract

A link between hypertension and long-term bone health has been suggested. The aim of this study was to investigate the effects of chronic angiotensin II administration on urinary calcium/phosphate excretion, bone mineral density, bone remodeling and osteoblast population in a well-established experimental model of hypertension, in the absence of possible confounding factors that could affect bone metabolism. Male Sprague-Dawley rats, divided in the following groups: (a) Angiotensin II (Ang II, 200 ng/kg/min, osmotic minipumps, sub cutis,

Indexed as

angiotensin IIboneexperimental hypertensionrats

Identifiers

PMID36428495
PMCPMC9687632
OpenAlexW4309215507

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.