ArticleAnimals : an open access journal from MDPI2022
Effects of Cisatracurium in Sevoflurane and Propofol Requirements in Dog-Undergoing-Mastectomy Surgery.
Article in Animals : an open access journal from MDPI, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06275087 (Differences in Speed of Recovery From Anesthesia and Recovery of Muscle Strength in General Balanced Inhalation Anesthesia and Total Intravenous Anesthesia for Intraoral Surgery - Clinical Randomised Trial), which is not on this map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Differences in Speed of Recovery From Anesthesia and Recovery of Muscle Strength in General Balanced Inhalation Anesthesia and Total Intravenous Anesthesia for Intraoral Surgery - Clinical Randomised Trial
Who cites it
14 citing papers in PubMed, 16 citations in OpenAlex.
- Effects of Topical Administration of Bupivacaine HCl to the Ovarian Pedicle on Postoperative Pain, Antioxidant Enzyme Activity and Inflammatory Cytokines in Dogs Undergoing Laparoscopic Ovariectomy.Veterinary medicine and science · 2026Article
- Evaluation of the effects of a single bolus of cisatracurium as part of an anesthetic protocol in cats undergoing orthopedic surgery.BMC veterinary research · 2026Article
- Ovariectomy in Canine Surgical Medicine: A Comparative Analysis of Surgical Approaches and the Nociceptive, Inflammatory, and Oxidative Stress Responses.Animals : an open access journal from MDPI · 2025Article
- Echocardiography and cardiorespiratory changes post ketofol or atracurium/ketofol on acepromazine-methadone premedicated dogs.Scientific reports · 2025Article
- Perioperative Pain Management for Mastectomy in Dogs: A Narrative Review.Animals : an open access journal from MDPI · 2025Review
- Effects of Progesterone on Isoflurane Requirement for Balance Disturbance and Loss of Righting Reflex in Male Mice.Cureus · 2024Article
- Oxidative stress in relation to serotonin under general anaesthesia in dogs undergoing ovariectomy.The veterinary quarterly · 2024Article
- Comparison Between Medetomidine and a Medetomidine-Vatinoxan Combination on Cardiorespiratory Variables in Dogs Undergoing Ovariectomy Anesthetized with Butorphanol, Propofol and Sevoflurane or Desflurane.Animals : an open access journal from MDPI · 2024Article
- Effect of surgery on oxidative stress and endogenous tocopherol concentrations in juvenile female dogs.Acta veterinaria Scandinavica · 2024Article
- Intraoperative Isoflurane End-Tidal Concentration during Infusion of Fentanyl, Tramadol, or Fentanyl-Tramadol Combination in Cats.Veterinary sciences · 2024Article
- Tramadol vs. Lidocaine Administered Intraperitoneally and in Incisional Lines for the Intraoperative and Postoperative Pain Management of Romifidine-Telazol-Anesthetized Swine Undergoing Umbilical Hernia Repair.Animals : an open access journal from MDPI · 2023Article
- Tramadol Administered Intravenously Either as a Bolus or a Slow Injection in Pain Management of Romifidine-Sedated Calves Undergoing Umbilical Hernia Repair.Animals : an open access journal from MDPI · 2023Article
- Levobupivacaine Combined with Cisatracurium in Peribulbar Anaesthesia in Cats Undergoing Corneal and Lens Surgery.Animals : an open access journal from MDPI · 2023Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The purpose of the present study was to test whether the addition of cisatracurium in combination with propofol and sevoflurane would result in a change in doses of used anesthetic drugs. Ten dogs (Group A) undergoing elective unilateral mastectomy surgery were included in the study. To induce and maintain anesthesia, subjects received propofol and sevoflurane at varying doses; analgesia was performed with remifentanil. After three months, the same subjects (Group B) underwent contralateral mastectomy and received the same anesthetic protocol with the addition of cisatracurium at a dosage of 0.2 mg/kg−1. The following parameters were monitored during anesthesia: heart rate, systolic blood pressure, end-tidal CO2, oxygen saturation, halogenate requirement, and rectal temperature at baseline (T0), induction (T1), 5 (T5), 10 (T10), 15 (T15), 20 (T20), 25 (T25), 30 (T30), and 35 (T35) time points. In Group A, halogenate requirement was reduced at all the time points other than T1 (p < 0.001); in Group B, the percentage of halogenate requirement was already reduced at T1 and remained constant during the experimental period, showing no significant intragroup differences. The dose requirements of sevoflurane and propofol varied significantly between the two groups, with significantly lower dosages in the Group B (the cisatracurium-treated group). Moreover, patients treated with cisatracurium showed a stable anesthetic plan. The nondepolarizing-muscle-relaxant cisatracurium besylate could be considered a useful adjunct to anesthetic protocols.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.