Evidence map›Paper›PMID 36428176›Full record

ArticleReproductive biomedicine online2023

Thrombocytopaenia and COVID-19 infection during pregnancy increases the risk of preeclampsia: a multicentre study.

Marta Defez-Martin, María Inmaculada Martín-Díaz, Sandra Atienza-Ramirez, Francisco Llorca-Colomer, Maria Teresa Murillo-Llorente, Marcelino Perez-Bermejo

Open access · greenAbstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Reproductive biomedicine online, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Marta Defez-MartinSchool of Medicine and Health Sciences, Catholic University of Valencia, Calle Quevedo, 2, Valencia 46001, Spain.
María Inmaculada Martín-DíazHospital Clínico Universitario de Valencia, Valencia, Spain.
Sandra Atienza-RamirezHospital Universitario Dr Peset, Valencia, Spain.
Francisco Llorca-ColomerSONEV Research Group, School of Medicine and Health Sciences, Catholic University of Valencia, Calle Quevedo, 2, Valencia 46001, Spain.
Maria Teresa Murillo-LlorenteSONEV Research Group, School of Medicine and Health Sciences, Catholic University of Valencia, Calle Quevedo, 2, Valencia 46001, Spain.
Marcelino Perez-BermejoSONEV Research Group, School of Medicine and Health Sciences, Catholic University of Valencia, Calle Quevedo, 2, Valencia 46001, Spain. Electronic address: marcelino.perez@ucv.es.
Valencia Catholic University Saint Vincent Martyr · ESHospital Clínico Universitario de Valencia · ESHospital Universitario Doctor Peset · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

research questionIs a low platelet count related to an increased risk of severe disease in pregnant women with active severe acute respiratory syndrome coronavirus 2 infection?

designA cross-sectional multicentre study in pregnant women with COVID-19 confirmed by polymerase chain reaction, antigen test, antibody test, or all.

resultsA total of 153 pregnant women with COVID-19 were included in the study, of whom 12.4% had thrombocytopaenia. Pregnant women with thrombocytopaenia were on average 3.1 years older (95% CI 0.18 to 6.38) than women without thrombocytopaenia. Pregnant smokers had a higher risk of thrombocytopaenia than non-smokers (OR 6.55, CI 95% 1.29 to 33.13). B Rh negative (B Rh-) pregnant women had a much higher risk of thrombocytopaenia than pregnant women with other blood groups (OR 16.83, CI 95% 1.42 to 199.8). Pregnant women with thrombocytopaenia had a much higher risk of suffering from preeclampsia (OR 16.2, CI 95% 1.35 to 193.4).

conclusionsCOVID-19 infection is not a risk factor for a low platelet count in pregnant women, although the risk is increased by smoking and in women with blood group B Rh-. In case of pregnancy with thrombocytopaenia, COVID-19 infection leads to an increased risk of preeclampsia.

Indexed as

COVID-19Pre-EclampsiaPregnancy Complications, InfectiousThrombocytopeniaCross-Sectional StudiesFemaleHumansPregnancy

Identifiers

PMID36428176
PMCPMC9637046
OpenAlexW4308318721

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.