Evidence map›Paper›PMID 36427650›Full record

ArticleJournal of affective disorders2023

Deconstructing resilience in patients at high risk for suicidal behavior.

Rachel Hendricks, John G Keilp, Mohammad Lesanpezeshki, Rina Muqkurtaj, Steven P Ellis, Hanga Galfalvy, Ainsley K Burke, Nadine Melhem, J John Mann

Abstract read
In one paragraph

Article in Journal of affective disorders, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Rachel HendricksDepartment of Molecular Imaging and Neuropathology, New York State Psychiatric Institute, New York, NY, United States of America; Department of Psychiatry, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, United States of America. Electronic address: rachel.hendricks@nyspi.columbia.edu.
John G KeilpDepartment of Molecular Imaging and Neuropathology, New York State Psychiatric Institute, New York, NY, United States of America; Department of Psychiatry, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, United States of America.
Mohammad LesanpezeshkiDepartment of Molecular Imaging and Neuropathology, New York State Psychiatric Institute, New York, NY, United States of America; Department of Psychiatry, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, United States of America.
Rina MuqkurtajDepartment of Molecular Imaging and Neuropathology, New York State Psychiatric Institute, New York, NY, United States of America; Department of Psychiatry, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, United States of America.
Steven P EllisDepartment of Molecular Imaging and Neuropathology, New York State Psychiatric Institute, New York, NY, United States of America; Department of Psychiatry, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, United States of America.
Hanga GalfalvyDepartment of Molecular Imaging and Neuropathology, New York State Psychiatric Institute, New York, NY, United States of America; Department of Psychiatry, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, United States of America.
Ainsley K BurkeDepartment of Molecular Imaging and Neuropathology, New York State Psychiatric Institute, New York, NY, United States of America; Department of Psychiatry, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, United States of America.
Nadine MelhemDepartment of Molecular Imaging and Neuropathology, New York State Psychiatric Institute, New York, NY, United States of America; Department of Psychiatry, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, United States of America.
J John MannDepartment of Molecular Imaging and Neuropathology, New York State Psychiatric Institute, New York, NY, United States of America; Department of Psychiatry, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, United States of America.

Funding

1/2 Inflammation and Stress Response in Familial and Nonfamilial Youth Suicidal BehaviorR01MH108039 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Nadine M. Melhem · 2015 to 2026
$3.2M
2/2 - Inflammation and Stress Response in Familial and Nonfamilial Youth Suicidal BehaviorR01MH108032 · NIMH · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI MANN, JOSEPH JOHN · 2015 to 2023
$2.7M
NIMH NIH HHS R01 MH108032NIMH NIH HHS R01 MH108039
6 · The paper itself

Abstract

backgroundResilience represents coping abilities to overcome exposure to psychopathological risk. In the context of risk factors for suicidal behavior, it is unknown if this attribute is deficient in suicide attempters, how it relates to other measures of risk, and where it may overlap with other risk factors associated with suicidal behavior.

methodsThe present study examined the performance on the Connor-Davidson Resilience Scale (CD-RISC) in three groups of individuals with familial risk for both mood disorder and suicidal behavior, as well as a healthy comparison group. Other risk factors for suicidal behavior, such as depression severity, hopelessness, and lifetime impulsiveness were examined as well to determine if these mediated group differences in CD-RISC scores.

resultsCD-RISC scores differed between groups, with lowest scores in the past attempter group. However, CD-RISC scores were strongly correlated with other common risk factors for suicide attempt, including hopelessness, subjective depression, and reasons for living, which together explained 68 % of the CD-RISC variance. Group differences in CD-RISC scores were eliminated when the model included these covariates. LIMITATIONS: Sample sizes were modest, and depression severity was low overall and significantly higher in the past suicide attempter group.

conclusionsThe CD-RISC has demonstrated utility for predicting risk for depression, but appears to overlap with other known risk factors for suicidal behavior, especially hopelessness and subjective depression. Though it encapsulates variance from multiple risk factors in a single scale, it may not provide additional predictive power above and beyond these other risk factors for suicidal behavior.

Indexed as

Resilience, PsychologicalSuicidal IdeationAdaptation, PsychologicalAffectHumansSelf ConceptSuicide, AttemptedDepressionResilienceRisk for suicideSuicide

Identifiers

PMID36427650
PMCPMC9945908

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.