Evidence map›Paper›PMID 36427155›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2023

Investigating Tissue Regeneration Using the DUAL Control Genetic Ablation System.

R E Harris

Abstract read
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In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

R E HarrisSchool of Life Sciences, Arizona State University, Tempe, AZ, USA. Robin.Harris@asu.edu.

Funding

Understanding Necrosis-Induced Tissue RegenerationR01GM147615 · NIGMS · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI Robin Harris · 2022 to 2026
$1.6M
The regenerative response to tissue necrosisR21HD102765 · NICHD · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI HARRIS, ROBIN · 2020 to 2021
$409k
NICHD NIH HHS R21 HD102765NIGMS NIH HHS R01 GM147615
6 · The paper itself

Abstract

Genetic ablation is a highly efficient method to study regeneration in vivo by stimulating tissue-specific cell death that subsequently induces regrowth and repair in a developing organism. This approach has been particularly successful in Drosophila, for which various temperature-based genetic ablation tools have been developed to explore the complexities of regeneration in larval imaginal discs. Here, we describe the use of a recently established ablation system called DUAL Control, which can be used to both characterize the damage response and genetically manipulate blastema cells to identify novel regulators of regeneration.

Indexed as

Drosophila ProteinsImaginal DiscsAnimalsDrosophilaLarvaWound HealingDrosophila ProteinsDrosophilaGene regulationGeneticsRepairScreeningTissue regenerationWound healing

Identifiers

PMID36427155

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.