ReviewClinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico2023
Peritumoral edema in meningiomas: pathophysiology, predictors, and principles for treatment.
Review in Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
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Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 20 citations in OpenAlex.
- European Association of Neuro-Oncology guideline on molecular testing of meningiomas for targeted therapy selection.Neuro-oncology · 2025Guideline
- Predictors of early and late postoperative seizures in meningioma patients: a systematic review and meta-analysis.Neurosurgical review · 2024Pooled it
- FOXC1 as a molecular predictor of postoperative peritumoral edema resolution in meningiomas.Journal of neuro-oncology · 2026Article
- FOXC1 expression and radiological predictors of peritumoral brain edema in meningiomas.Journal of neuro-oncology · 2026Article
- Optimal α/β Ratio for Biologically Effective Dose-Based Prediction of Radiation-Induced Peritumoral Brain Edema in Meningioma.Cancers · 2026Article
- Deficiency of SMARCB1 drives an immunosuppressive microenvironment in meningioma.Acta neuropathologica communications · 2026Article
- Topological feature-driven TabPFN model for prediction of enlarged hemorrhage and edema after tumor resection in meningiomas.Frontiers in medicine · 2026Article
- Hidden Culprit: Stroke-Like Presentation and Seizure Reveal Parasagittal Meningioma: A Case Report.Clinical medicine insights. Case reports · 2026Article
- Peritumoral edema in meningiomas: a review of influencing factors, mechanisms, and management.Frontiers in oncology · 2026Review
- Peritumoral Edema in Canine Extra-Axial Brain Tumours: Effect of Steroids.Veterinary and comparative oncology · 2025Article
- Article
- Peritumoral MRI findings and brain herniations in epileptic dogs with prosencephalic brain tumors: a multicentre retrospective study.Frontiers in veterinary science · 2025Article
- Radiographic predictors of peritumoral brain edema in intracranial meningiomas: a review of current controversies and illustrative cases.Chinese neurosurgical journal · 2024Review
- Development of a clinical-radiological nomogram for predicting severe postoperative peritumoral brain edema following intracranial meningioma resection.Frontiers in neurology · 2024Article
- Case Report: Recurrent meningioma with multiple metastases.Frontiers in oncology · 2023Article
Corrections and comments
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Authors and funding
7 authors at 6 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Meningiomas is a tumor of the meninges and is among the most common intracranial neoplasms in adults, accounting for over a third of all primary brain tumors in the United States. Meningiomas can be associated with peritumoral brain edema (PTBE) which if not managed appropriately can lead to poor clinical outcomes. In this review, we summarize the relevant pathophysiology, predictors, and principles for treatment of PTBE. The results of various case-reports and case-series have found that meningioma-associated PTBE have patterns in age, tumor size, and hormone receptor positivity. Our study describes how increased age, increased tumor size, tumor location in the middle fossa, and positive expression of hormone receptors, VEGF, and MMP-9 can all be predictors for worse clinical outcomes. We also characterize treatment options for PTBE such as glucocorticoids and VEGF inhibitors along with the ongoing clinical trials attempting to alleviate PTBE in meningioma cases. The trends summarized in this review can be used to better predict the behavior of meningioma-associated PTBE and establish prognosis models to identify at risk patients.
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