SynthesisPediatric nephrology (Berlin, Germany)2023
Relationship between nocturnal enuresis and sleep in children and adolescents.
Synthesis in Pediatric nephrology (Berlin, Germany), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.
- Obstructive sleep apnea and nocturnal enuresis in the pediatric population: a systematic review and meta-analysis.Sleep & breathing = Schlaf & Atmung · 2026Pooled it
- Sleep Parameters and Motor Activity in Children With Nocturnal Enuresis and Daytime Urinary Incontinence.Neurourology and urodynamics · 2026Article
- Objective sleep parameters in children with nocturnal enuresis: a scoping review of polysomnographic evidence.European journal of pediatrics · 2026Article
- Relationship Between Obstructive Sleep Apnea and Enuresis in Children: Current Perspectives and Beyond.Nature and science of sleep · 2025Review
- Sleep duration, sleep problems and developmental trajectories of urinary incontinence: a prospective cohort study.European child & adolescent psychiatry · 2024Article
- Logistic regression analysis of risk factors influencing childhood enuresis: a comprehensive survey study.American journal of translational research · 2024Article
- Application of non-invasive neuromodulation in children with neurodevelopmental disorders to improve their sleep quality and constipation.BMC pediatrics · 2023Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNocturnal enuresis (NE) is a multifactorial and complex condition. One less understood factor in its pathophysiology is the enuretic inability to wake up when the bladder is full (impaired arousal).
objectiveWe aimed to investigate the relationship between sleep and NE in children and adolescents.
methodsA systematic review was performed following the PRISMA guidelines, and the electronic databases MEDLINE (via PubMed) and SCOPUS were searched until March 2022. Eligibility criteria were studies that recruited patients aged five-17 years with a diagnosis of NE according to the International Child Continence Society (ICCS), Diagnostic and Statistical Manual of Mental Disorders-Fifth Edition (DSM-5), or International Classification Criteria of Sleep Disorders-Third edition (ICSD-3) who had their sleep assessed using validated questionnaires and/or polysomnography. The tool used to analyze the risk of bias in the included studies was the risk of bias in non-randomized studies of exposure.
resultsOf 1582 citations screened, nine were included, giving 1685 participants, 581 with NE. All studies were observational and half had a low risk of bias. Four studies evaluated sleep by questionnaires only; two used questionnaires and polysomnography; two used only polysomnography, and one used sleep logs and actigraphy. Sleep questionnaires showed that children with enuresis had more sleep problems than controls, especially parasomnias, breathing disorders, and daytime sleepiness. Among the polysomnography parameters, the sleep stage architecture and periodic limb movements during sleep had conflicting data between the two studies. LIMITATIONS: The studies evaluated sleep through heterogeneous tools. They used different questionnaires; even those considered by polysomnography did not record the same channels.
conclusionIt seems that enuretic children and adolescents sleep differently from those who are non-enuretic. More studies are needed to clarify the best way to assess sleep and better understand this relationship. The review protocol was registered with PROSPERO, CRD42021266338. There was no funding.
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