Evidence map›Paper›PMID 36427055›Full record

ArticleThe British journal of radiology2023

Mid-term follow-up chest CT findings in recovered COVID-19 patients with residual symptoms.

Francesca Marchetti, Nicoletta Izzi, Antonella Donatelli, Adele Valentini, Shaun Ivan Muzic, Roberto Dore, Antonio Di Sabatino, Tiziano Perrone, Francesco Falaschi, Umberto Sabatini and 10 more

Open access · bronzeAbstract read
In one paragraph

Article in The British journal of radiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 3 institutions in 1 country.

Francesca MarchettiDepartment of Clinical, Surgical, Diagnostic and Pediatric Sciences, University of Pavia, Pavia, Italy.
Nicoletta IzziDepartment of Clinical, Surgical, Diagnostic and Pediatric Sciences, University of Pavia, Pavia, Italy.
Antonella DonatelliDepartment of Clinical, Surgical, Diagnostic and Pediatric Sciences, University of Pavia, Pavia, Italy.
Adele ValentiniRadiology Institute, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Shaun Ivan MuzicDepartment of Clinical, Surgical, Diagnostic and Pediatric Sciences, University of Pavia, Pavia, Italy.
Roberto DoreRadiology Unit, Cinical Institute Città di Pavia, Pavia, Italy.
Antonio Di SabatinoDepartment of Internal Medicine, Fondazione I.R.C.C.S. Policlinico San Matteo, University of Pavia, Pavia, Italy.
Tiziano PerroneDepartment of Internal Medicine, Fondazione I.R.C.C.S. Policlinico San Matteo, University of Pavia, Pavia, Italy.
Francesco FalaschiInternal Medicine 2, Fondazione IRCCS Policlinico San Matteo, University of Pavia, Pavia, Italy.
Umberto SabatiniDepartment of Internal Medicine, Fondazione I.R.C.C.S. Policlinico San Matteo, University of Pavia, Pavia, Italy.
Alessia BallesioDepartment of Internal Medicine, Fondazione I.R.C.C.S. Policlinico San Matteo, University of Pavia, Pavia, Italy.
Federica MeloniUniversity of Pavia and Pneumology Unit, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Sara LettieriDepartment of Anesthesia, Intensive Care and Pain Therapy, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Francesco MojoliDepartment of Clinical, Surgical, Diagnostic and Pediatric Sciences, University of Pavia, Pavia, Italy.
Stefano PerliniDepartment of Internal Medicine, Fondazione I.R.C.C.S. Policlinico San Matteo, University of Pavia, Pavia, Italy.
Stefano NovatiDepartment of Infectious Diseases, Fondazione IRCCS Policlinico San Matteo, University of Pavia, Pavia, Italy.
Elisabetta PaganiDepartment of Infectious Diseases, Fondazione IRCCS Policlinico San Matteo, University of Pavia, Pavia, Italy.
Catherine KlersyClinic Epidemiology and Biometry Unit, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Raffaele BrunoDepartment of Clinical, Surgical, Diagnostic and Pediatric Sciences, University of Pavia, Pavia, Italy.
Lorenzo PredaDepartment of Clinical, Surgical, Diagnostic and Pediatric Sciences, University of Pavia, Pavia, Italy.
University of Pavia · ITPoliclinico San Matteo Fondazione · ITIstituti di Ricovero e Cura a Carattere Scientifico · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesMore than a year has passed since the initial outbreak of SARS-CoV-2, which caused many hospitalizations worldwide due to COVID-19 pneumonia and its complications. However, there is still a lack of information detailing short- and long-term outcomes of previously hospitalized patients. The purpose of this study is to analyze the most frequent lung CT findings in recovered COVID-19 patients at mid-term follow-ups.

methodsA total of 407 consecutive COVID-19 patients who were admitted to the Fondazione IRCCS Policlinico San Matteo, Pavia and discharged between February 27, 2020, and June 26, 2020 were recruited into this study. Out of these patients, a subset of 108 patients who presented with residual asthenia and dyspnea at discharge, altered spirometric data, positive lung ultrasound and positive chest X-ray was subsequently selected, and was scheduled to undergo a mid-term chest CT study, which was evaluated for specific lung alterations and morphological patterns.

resultsThe most frequently observed lung CT alterations, in order of frequency, were ground-glass opacities (81%), linear opacities (74%), bronchiolectases (64.81%), and reticular opacities (63.88%). The most common morphological pattern was the non-specific interstitial pneumonia pattern (63.88%). Features consistent with pulmonary fibrosis were observed in 32 patients (29.62%).

conclusionsOur work showed that recovered COVID-19 patients who were hospitalized and who exhibited residual symptoms after discharge had a slow radiological recovery with persistent residual lung alterations. ADVANCES IN KNOWLEDGE: This slow recovery process should be kept in mind when determining the follow-up phases in order to improve the long-term management of patients affected by COVID-19.

Indexed as

COVID-19COVID-19 TestingFollow-Up StudiesHumansLungRetrospective StudiesSARS-CoV-2Tomography, X-Ray Computed

Identifiers

PMID36427055
PMCPMC10997016
OpenAlexW4310053046

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.