ArticleHuman brain mapping2023
A subcortical magnocellular pathway is responsible for the fast processing of topological properties of objects: A transcranial magnetic stimulation study.
Article in Human brain mapping, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.
- Meta-analysis of experimental factors influencing single-pulse TMS effects on the early visual cortex.Frontiers in neuroscience · 2024Pooled it
- I Can't Hear You Both at the Same Time: A Temporal Dilemma During Inter-Regional Communication.eNeuro · 2026Article
- Causal evidence for dorsal stream involvement in object shape recognition: A tractography-guided ccPAS Registered Report study.Imaging neuroscience (Cambridge, Mass.) · 2026Article
- CognivueJournal of Alzheimer's disease : JAD · 2025Article
- Reduced Attentional Capture by Topological Changes in Children with Autism Spectrum Disorder: Evidence for a Perceptual Deficit.Neuropsychiatric disease and treatment · 2025Article
- Investigating the hemiretinal asymmetry in emotion processing as a function of spatial frequency.Proceedings. Biological sciences · 2024Article
- Object-based attention requires monocular visual pathways.Psychonomic bulletin & review · 2024Article
- Deficits of the "Good" Eye in Amblyopia: Processing Geometric Properties.Investigative ophthalmology & visual science · 2024Article
- A subcortical magnocellular pathway is responsible for the fast processing of topological properties of objects: A transcranial magnetic stimulation study.Human brain mapping · 2023Article
- Temporal asymmetries and interactions between dorsal and ventral visual pathways during object recognition.Cerebral cortex communications · 2023Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Rapid object recognition has survival significance. The extraction of topological properties (TP) is proposed as the starting point of object perception. Behavioral evidence shows that TP processing takes precedence over other geometric properties and can accelerate object recognition. However, the mechanism of the fast TP processing remains unclear. The magnocellular (M) pathway is well known as a fast route to convey "coarse" information, compared with the slow parvocellular (P) pathway. Here, we hypothesize that the fast processing of TP occurs in a subcortical M pathway. We applied single-pulse transcranial magnetic stimulation (TMS) over the primary visual cortex to temporarily disrupt cortical processing. Besides, stimuli were designed to preferentially engage M or P pathways (M- or P-biased conditions). We found that, when TMS disrupted cortical function at the early stages of stimulus processing, non-TP shape discrimination was strongly impaired in both M- and P-biased conditions, whereas TP discrimination was not affected in the M-biased condition, suggesting that early M processing of TP is independent of the visual cortex, but probably occurs in a subcortical M pathway. Using an unconscious priming paradigm, we further found that early M processing of TP can accelerate object recognition by speeding up the processing of other properties, e.g., orientation. Our findings suggest that the human visual system achieves efficient object recognition by rapidly processing TP in the subcortical M pathway.
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