Evidence map›Paper›PMID 36426792›Full record

ArticleDevelopmental psychobiology2022

Assessment of the effects of sex, age, and rearing condition on ultrasonic vocalizations elicited by pups during the maternal potentiation paradigm in C57BL/6J mice.

Danielle Santana-Coelho, Paige D Womble, Katherine J Blandin, Jacob B Pilcher, Grace M O'Neill, Leighton A Douglas, Srikhar V Chilukuri, Doan L K Tran, Taylor A Wiley, Joaquin N Lugo

Open access · hybridAbstract read
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In one paragraph

Article in Developmental psychobiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Danielle Santana-CoelhoDepartment of Psychology and Neuroscience, Baylor University, Waco, Texas, USA.ORCID 0000-0003-3784-2036
Paige D WombleDepartment of Psychology and Neuroscience, Baylor University, Waco, Texas, USA.
Katherine J BlandinDepartment of Psychology and Neuroscience, Baylor University, Waco, Texas, USA.
Jacob B PilcherDepartment of Psychology and Neuroscience, Baylor University, Waco, Texas, USA.ORCID 0000-0002-0992-8281
Grace M O'NeillDepartment of Psychology and Neuroscience, Baylor University, Waco, Texas, USA.
Leighton A DouglasDepartment of Psychology and Neuroscience, Baylor University, Waco, Texas, USA.ORCID 0000-0002-1319-3505
Srikhar V ChilukuriDepartment of Psychology and Neuroscience, Baylor University, Waco, Texas, USA.
Doan L K TranDepartment of Psychology and Neuroscience, Baylor University, Waco, Texas, USA.
Taylor A WileyDepartment of Psychology and Neuroscience, Baylor University, Waco, Texas, USA.ORCID 0000-0002-0664-7249
Joaquin N LugoDepartment of Psychology and Neuroscience, Baylor University, Waco, Texas, USA.ORCID 0000-0001-6874-8718
Baylor University · US

Funding

Signaling Mechanisms Underlying Epilepsy and Autism CormorbidityR15NS088776 · NINDS · BAYLOR UNIVERSITY · PI JOAQUIN N LUGO · 2015 to 2026
$1.8M
NINDS NIH HHS R15 NS088776
6 · The paper itself

Abstract

Isolation-induced ultrasonic vocalizations (USVs) are important to elicit parental retrieval. This behavior is critical for the animal's survival and can be altered in models of developmental disorders. The potentiation of vocalizations in response to reunion with the dam, also called maternal potentiation, has been extensively studied in rats. However, the assessment of this paradigm in mice is scarce. In rats, the potentiation of vocalizations is dependent on rearing conditions. Since mice are the main species used for genetic models of diseases, we aimed to investigate how different factors such as age, sex, and rearing conditions can affect the potentiation of vocalizations in the maternal potentiation paradigm in mice. We carried out experiments using biparental (dam and sire) or uniparental rearing (dam). Pups were tested on postnatal days (PD) 9 or 12. Pups showed increased potentiation in both sexes at PD9 with uniparental rearing. Both rearing conditions and ages changed the repertoire from the first to the second isolation. Spectral parameters were affected by sex, rearing condition and reunion at PD9. At PD12, only duration was altered by reunion. We conclude that the performance of the pups in the maternal potentiation paradigm is dependent on age, sex, and rearing condition.

Indexed as

UltrasonicsVocalization, AnimalAnimalsFamilyFemaleMaleMiceMice, Inbred C57BLRatsmaternal potentiationmicerearingrepertoireultrasonic vocalizations

Identifiers

PMID36426792
PMCPMC9828101
OpenAlexW4309083100

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.