Evidence map›Paper›PMID 36426730›Full record

ArticleMagnetic resonance in medicine2023

Uncertainty-aware physics-driven deep learning network for free-breathing liver fat and R

Shu-Fu Shih, Sevgi Gokce Kafali, Kara L Calkins, Holden H Wu

Open access · greenAbstract read
In one paragraph

Article in Magnetic resonance in medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Rapid, high-resolution and distortion-freeMagnetic resonance in medicine · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Free-breathing MRI techniques for fat and RMagma (New York, N.Y.) · 2024
    Review
  9. Article
  10. Review
  11. Deep Learning-accelerated MRI in Body and Chest.Journal of computer assisted tomography
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Shu-Fu ShihDepartment of Radiological Sciences, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, USA.ORCID 0000-0002-3812-9091
Sevgi Gokce KafaliDepartment of Radiological Sciences, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, USA.ORCID 0000-0001-5941-5399
Kara L CalkinsDepartment of Pediatrics, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, USA.ORCID 0000-0001-6658-7981
Holden H WuDepartment of Radiological Sciences, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, USA.ORCID 0000-0002-2585-5916
University of California, Los Angeles · US

Funding

UCLA Clinical Translational Science InstituteUL1TR001881 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ARLEEN F. BROWN, ARASH NAEIM · 2016 to 2026
$118.1M
Quantifying Body Composition and Liver Disease in Children using Free-Breathing MRI and MRER01DK124417 · NIDDK · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI CALKINS, KARA LYNNE, WU, HOLDEN H · 2020 to 2023
$2.3M
NCATS NIH HHS UL1 TR001881NCATS NIH HHS UL1TR001881NIDDK NIH HHS R01 DK124417
6 · The paper itself

Abstract

purposeTo develop a deep learning-based method for rapid liver proton-density fat fraction (PDFF) and R

methodsThis work developed an uncertainty-aware physics-driven deep learning network (UP-Net) to (1) suppress radial streaking artifacts because of undersampling after self-gating, (2) calculate accurate quantitative maps, and (3) provide pixel-wise uncertainty maps. UP-Net incorporated a phase augmentation strategy, generative adversarial network architecture, and an MRI physics loss term based on a fat-water and R

resultsCompared with images reconstructed using compressed sensing (CS), UP-Net achieved structural similarity index >0.87 and normalized root mean squared error <0.18. Compared with reference quantitative maps generated using CS and graph-cut (GC) algorithms, UP-Net achieved low mean differences (MD) for liver PDFF (-0.36%) and R

conclusionUP-Net rapidly calculates accurate liver PDFF and R

Indexed as

Deep LearningHumansImage Interpretation, Computer-AssistedLiverMagnetic Resonance ImagingProtonsUncertaintyProtonsdeep learning reconstructiondeep learning uncertaintyfree-breathing radial MRIliverproton-density fat fractionR2*

Identifiers

PMID36426730
PMCPMC9892263
OpenAlexW4309938080

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.