Evidence map›Paper›PMID 36426398›Full record

ArticleAllergy, asthma & immunology research2022

Altered Expression of Substance P and NK1R in CCR3

Shiyang Geng, Hua Xie, Liping Chen, Dong Chen, Sijing Lu, Nan Zhao, Ruiming Yang, Zhao Wang, Shaoheng He, Huiyun Zhang

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Allergy, asthma & immunology research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Shiyang GengAllergy and Clinical Immunology Research Centre, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, China.ORCID https://orcid.org/0000-0002-0931-743X
Hua XieDepartment of the PLA Center of Respiratory and Allergic Disease Diagnosing Management, General Hospital of Northern Theater Command, Shenyang, China.ORCID https://orcid.org/0000-0003-4904-0698
Liping ChenTranslational Medicine Research Centre, Shenyang Medical College, Shenyang, China.ORCID https://orcid.org/0000-0003-0285-4897
Dong ChenAllergy and Clinical Immunology Research Centre, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, China.ORCID https://orcid.org/0000-0002-9260-4455
Sijing LuAllergy and Clinical Immunology Research Centre, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, China.ORCID https://orcid.org/0000-0002-5781-0958
Nan ZhaoAllergy and Clinical Immunology Research Centre, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, China.ORCID https://orcid.org/0000-0002-6558-7506
Ruiming YangAllergy and Clinical Immunology Research Centre, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, China.ORCID https://orcid.org/0000-0002-5513-5397
Zhao WangAllergy and Clinical Immunology Research Centre, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, China.ORCID https://orcid.org/0000-0002-6819-4484
Shaoheng HeAllergy and Clinical Immunology Research Centre, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, China.ORCID https://orcid.org/0000-0003-4760-4816
Huiyun ZhangAllergy and Clinical Immunology Research Centre, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, China.ORCID https://orcid.org/0000-0003-0631-3000
Jinzhou Medical University · CNShenyang Medical College · CNAffiliated Hospital of Jining Medical University · CNGeneral Hospital of Shenyang Military Region · CN

Funding

Boze Project of Jinzhou Medical University JYBZQT2110Climbing Scholar Project in Liaoning province 2018-38Innovation and Entrepreneurship Projects for High-Level Talent in Shenyang 2017CXCY-C-01Key Laboratory of Research on Pathogenesis of Allergen provoked Allergic Disease, Liaoning Province 2018-30Leader Team Project in Jinzhou Medical University 2017-2020Liaoning Province Science and Technology Planning project 2019JH8/10300053Liaoning Province Science and Technology Planning project 2021JH2/10300022Natural Science Foundation of Liaoning Province 2019-ZD-0801Natural Science Foundation of Liaoning Province LJKZ0796Science and Technology Innovation "double hundred project" in Shenyang Z17-5-044Shenyang Science and Technology Plan Project 19-109-4-17
6 · The paper itself

Abstract

purposeTo explore expression of SP and NK1R in basophils of allergic asthma (AA), allergic rhinitis (AR) and AR combined with AA (ARA), and influence of allergens and immunoglobulin E (IgE) mediated mechanisms on SP and NK1R expression.

methodsExpression of SP and NK1R was detected by flow cytometry, NK1R mRNA expression was detected by real time quantitative polymerase chain reaction (qPCR), and mouse AR and AA models were employed for in vivo study.

resultsSP

conclusionCCR3

Indexed as

allergenallergyasthmaIgEneurokinin 1 receptorrhinitisSubstance P

Identifiers

PMID36426398
PMCPMC9709683
OpenAlexW4310336188

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.