ArticleThe Lancet regional health. Europe2023
Presentation, management, and outcomes of cauda equina syndrome up to one year after surgery, using clinician and participant reporting: A multi-centre prospective cohort study.
Article in The Lancet regional health. Europe, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06416878 (Can Brief Perioperative Epidural Electrical Stimulation Improve Recovery of Autonomic Function in Cauda Equina Syndrome), which is not on this map. Cited by 21 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Can Brief Perioperative Epidural Electrical Stimulation Improve Recovery of Autonomic Function in Cauda Equina Syndrome
Who cites it
21 citing papers in PubMed, 44 citations in OpenAlex.
- Cauda equina syndrome: a structured approach for the higher orthopaedic examination.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2026Review
- The "Silent Disability"- examining patient perspectives on the diagnosis, management and the long-term implications of cauda equina syndrome in Ireland.Irish journal of medical science · 2026Article
- Sexual dysfunction after cauda equina syndrome: a systematic review of long-term outcomes.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Review
- Chiropractic spinal manipulative therapy versus physical therapist-led exercise and the risk of cauda equina syndrome in adults with lumbar disc herniation, stenosis, or radiculopathy.PM & R : the journal of injury, function, and rehabilitation · 2026Article
- Dural Sac Cross-Sectional Area Measurement as an Indicator of Cauda Equina Syndrome Risk in Patients with Lumbar Disc Herniation.Journal of clinical medicine · 2026Article
- Review
- Physiotherapist's Management of Suspected Cauda Equina Syndrome in the United Kingdom: A National Survey.Physiotherapy research international : the journal for researchers and clinicians in physical therapy · 2026Article
- Assessment of cauda equina syndrome: new national guidelines and implications for primary care.The British journal of general practice : the journal of the Royal College of General Practitioners · 2025Article
- From hospital discharge to long-term care: Unmet rehabilitation needs in cauda equina syndrome patients from a national UK cohort.World neurosurgery: X · 2025Article
- Cauda Equina Syndrome: A Survey of Guideline Utilisation in Primary Care in England.Musculoskeletal care · 2025Article
- Is out-of-hours decompression for acute lumbar disc herniation associated with greater peri-operative complications? A tertiary centre, retrospective cohort study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025Article
- Improving the suspected cauda equina syndrome pathway at a district general hospital: a quality improvement project.BMJ open quality · 2025Article
- The experience and need of patients with cauda equina syndrome caused by lumbar disc herniation: a phenomenological qualitative study.BMC musculoskeletal disorders · 2025Article
- Emergencies in inflammatory rheumatic diseases.Rheumatology international · 2024Review
- Identification and Assessment of Outcome Measurement Instruments in Cauda Equina Syndrome: A Systematic Review.Global spine journal · 2024Article
- Cauda equina, conus medullaris and syndromes mimicking sciatic pain: WFNS spine committee recommendations.World neurosurgery: X · 2024Review
- Recovery with posterior decompression and dural suturing in a patient with cauda equina syndrome caused by lamina entrapment in an unstable burst fracture: A case report.International journal of surgery case reports · 2024Article
- High-Riding Conus Medullaris Syndrome: A Case Report and Literature Review-Its Comparison with Cauda Equina Syndrome.Tomography (Ann Arbor, Mich.) · 2023Review
- More questions than answers to the diagnosis and management of cauda equina syndrome.The Lancet regional health. Europe · 2023Article
- More questions than answers to the diagnosis and management of cauda equina syndrome-Authors' reply.The Lancet regional health. Europe · 2023Article
Corrections and comments
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Authors and funding
23 authors at 12 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Cauda equina syndrome (CES) results from nerve root compression in the lumbosacral spine, usually due to a prolapsed intervertebral disc. Evidence for management of CES is limited by its infrequent occurrence and lack of standardised clinical definitions and outcome measures. Methods: This is a prospective multi-centre observational cohort study of adults with CES in the UK. We assessed presentation, investigation, management, and all Core Outcome Set domains up to one year post-operatively using clinician and participant reporting. Univariable and multivariable associations with the Oswestry Disability Index (ODI) and urinary outcomes were investigated. Findings: In 621 participants with CES, catheterisation for urinary retention was required pre-operatively in 31% (191/615). At discharge, only 13% (78/616) required a catheter. Median time to surgery from symptom onset was 3 days (IQR:1-8) with 32% (175/545) undergoing surgery within 48 h. Earlier surgery was associated with catheterisation (OR:2.2, 95%CI:1.5-3.3) but not with admission ODI or radiological compression. In multivariable analyses catheter requirement at discharge was associated with pre-operative catheterisation (OR:10.6, 95%CI:5.8-20.4) and one-year ODI was associated with presentation ODI (r = 0.3, 95%CI:0.2-0.4), but neither outcome was associated with time to surgery or radiological compression. Additional healthcare services were required by 65% (320/490) during one year follow up. Interpretation: Post-operative functional improvement occurred even in those presenting with urinary retention. There was no association between outcomes and time to surgery in this observational study. Significant healthcare needs remained post-operatively. Funding: DCN Endowment Fund funded study administration. Castor EDC provided database use. No other study funding was received.
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