ReviewFrontiers in cardiovascular medicine2022
Comprehensive functional and anatomic assessment of myocardial bridging: Unlocking the Gordian Knot.
Review in Frontiers in cardiovascular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06281067 (Reassessment of myocardIAL Bridge TOwards PeRsOnalized Medicine), which is not on this map. Cited by 11 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Reassessment of myocardIAL Bridge TOwards PeRsOnalized Medicine: RIALTO PRO
Who cites it
11 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Efficacy and safety of Traditional Chinese Medicine in alleviating symptoms associated with myocardial bridge: a systematic review and meta-analysis.Frontiers in pharmacology · 2025Pooled it
- A Contemporary Review of the Genomic Associations of Coronary Artery Myocardial Bridging.Genes · 2023Pooled it
- Coronary Artery Anomalies and Anatomical Variants: Cross-Sectional Diagnostic Imaging and Clinical Background.Journal of imaging · 2026Review
- Review
- Real-world presentation of myocardial bridging in the cath-lab: a case series.European heart journal. Case reports · 2026Article
- Intramyocardial Bridge in Sports Medicine: Proposal of a Possible Follow-Up Strategy in Asymptomatic Athletes.Journal of functional morphology and kinesiology · 2026Article
- Antiplatelet Therapy in Myocardial Bridge: Insights From the RIALTO Registry.Journal of the American Heart Association · 2025Observational
- Unveiling the Causes of Acute and Non-Acute Myocardial Ischemic Syndromes: The Role of Optical Coherence Tomography.Medicina (Kaunas, Lithuania) · 2025Review
- Micro-coil embolization for transcatheter septal ablation in a hypertrophic obstructive cardiomyopathy patient and an unusual coronary anatomy: a case report.Frontiers in cardiovascular medicine · 2025Article
- The effects of myocardial bridging on two-dimensional myocardial strain during dobutamine stress echocardiography.The international journal of cardiovascular imaging · 2024Article
- High Prevalence of Myocardial Bridging Detected in an Indonesian Population Using Multi-Detector Computed Tomography.Medicina (Kaunas, Lithuania) · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Myocardial bridging (MB) is the most frequent congenital coronary anomaly in which a segment of an epicardial coronary artery takes a tunneled course under a bridge of the myocardium. This segment is compressed during systole, resulting in the so-called "milking effect" at coronary angiography. As coronary blood flow occurs primarily during diastole, the clinical relevance of MB is heterogeneous, being usually considered an asymptomatic bystander. However, many studies have suggested its association with myocardial ischemia, anginal symptoms, and adverse cardiac events. The advent of contemporary non-invasive and invasive imaging modalities and the standardization of intracoronary functional assessment tools have remarkably improved our understanding of MB-related ischemia, suggesting the role of atherosclerotic lesions proximal to MB, vasomotor disorders and microvascular dysfunction as possible pathophysiological substrates. The aim of this review is to provide a contemporary overview of the pathophysiology and of the non-invasive and invasive assessment of MB, in the attempt to implement a case-by-case therapeutic approach according to the specific endotype of MB-related ischemia.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.