Evidence map›Paper›PMID 36426165›Full record

ReviewArchives of academic emergency medicine2022

Diagnostic Performance of Magnetic Resonance Imaging for Detection of Acute Appendicitis in Pregnant Women; a Systematic Review and Meta-Analysis.

Mohsen Motavaselian, Fateme Bayati, Reza Amani-Beni, Amirreza Khalaji, Sara Haghverdi, Zeynab Abdollahi, Arash Sarrafzadeh, Amir-Masood Rafie Manzelat, Amir Rigi, Razman Arabzadeh Bahri and 12 more

Open access · greenAbstract readReview
In one paragraph

Review in Archives of academic emergency medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
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  10. Lessons Learned from Liver-on-Chip Platform.Annals of biomedical engineering · 2025
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  14. Current Research in Drug-Free Cancer Therapies.Bioengineering (Basel, Switzerland) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 13 institutions in 1 country.

Mohsen MotavaselianSchool of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Fateme BayatiUSERN Office, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Reza Amani-BeniSchool of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Amirreza KhalajiLiver and Gastrointestinal Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Sara HaghverdiKermanshah University of Medical Sciences, Kermanshah, Iran.
Zeynab AbdollahiAhvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Arash SarrafzadehSchool of Dentistry, Arak University of Medical Sciences, Arak, Iran.
Amir-Masood Rafie ManzelatSchool of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Amir RigiIslamic Azad University, Zahedan Branch, Zahedan, Iran.
Razman Arabzadeh BahriTehran University of Medical Sciences, Tehran, Iran.
Zahra NakhaeeGonabad University, Gonabad, Iran.
Mahta FadaeiSchool of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Hajar Ghasemi FalaverjaniDepartment of Internal Medicine, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Sara Malekpour-DehkordiAhvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Maryam HoseinpourAhvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Matin BidaresIslamic Azad University of Najafabad, Najafabad, Iran.
Sarvenaz ZandkarimiFaculty of Pharmacy, Islamic Azad University of Tehran Medical Sciences, Tehran, Iran.
Rasha AhmadiShariati Hospital, Tehran University of Medical Science, Tehran, Iran.
Dorsa BeheshtiparvarSchool of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Seyed-Amirabbas AhadiatResearch Center of Biochemistry and Nutrition in Metabolic Disorder, Kashan University of Medical science. Kashan, Iran.
Mohsen FarshiSchool of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Mehrdad FarrokhiMen's Health and Reproductive Health Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Isfahan University of Medical Sciences · IRAhvaz Jundishapur University of Medical Sciences · IRShahid Beheshti University of Medical Sciences · IRKermanshah University of Medical Sciences · IRArak University of Medical Sciences · IRIslamic Azad University of Najafabad · IRIslamic Azad University, Zahedan Branch · IRKashan University of Medical Sciences · IRShahid Sadoughi University of Medical Sciences and Health Services · IRShariati Hospital · IRTabriz University of Medical Sciences · IRTehran University of Medical Sciences · IRUniversity of Gonabad · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The diagnosis of acute appendicitis (AA) in pregnant women is commonly challenging owing to the normal results of laboratory tests, organ displacement, and normal physiological inflammatory alterations. This meta-analysis aimed to investigate the accuracy of magnetic resonance imaging (MRI) in diagnosis of AA in pregnant women. Methods: Two investigators independently performed a comprehensive systematic literature search of electronic databases including MEDLINE, Cochrane Central, EMBASE, Web of Science, Scopus, and Google Scholar to identify studies that reported accuracy of MRI for diagnosis of AA in pregnant women from inception to April 1, 2022. Results: Our systematic search identified a total of 525 published papers. Finally, a total of 26 papers were included in the meta-analysis. The pooled sensitivity and specificity of MRI in diagnosis of AA in pregnant women were 0.92 (95% CI: 0.88-0.95) and 0.98 (95% CI 0.97-0.98), respectively. The pooled positive likelihood ratio and negative likelihood ratio were 29.52 (95% CI: 21.90-39.81) and 0.10 (95% CI: 0.04-0.25), respectively. The area under hierarchical summary receiver operating characteristic (HSROC) curve indicated that the accuracy of MRI for diagnosis of AA in pregnant women is 99%. Conclusion: This meta-analysis showed that MRI has high sensitivity, specificity, and accuracy for diagnosis of AA in pregnant women and can be used as a first-line imaging modality for suspected cases of AA during pregnancy. Furthermore, it should be noted that when the result of ultrasonography is inconclusive, the use of MRI can reduce unnecessary appendectomy in pregnant patients.

Indexed as

Appendicitismagnetic resonance imagingmeta-analysispregnancy

Identifiers

PMID36426165
PMCPMC9676701
OpenAlexW4310330137

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.