Evidence map›Paper›PMID 36425686›Full record

ReviewRSC advances2022

Optical chemosensors for environmental monitoring of toxic metals related to Alzheimer's disease.

Islam M El-Sewify, Ahmed Radwan, Nehal H Elghazawy, Wolfgang Fritzsche, Hassan M E Azzazy

Open access · goldAbstract readReview
In one paragraph

Review in RSC advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 25 citations in OpenAlex.

  1. Valorization of BaCORSC advances · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Islam M El-SewifyDepartment of Chemistry, Faculty of Science, Ain Shams University 11566 Abbassia Cairo Egypt.ORCID https://orcid.org/0000-0003-1934-4260
Ahmed RadwanDepartment of Chemistry, Faculty of Science, Ain Shams University 11566 Abbassia Cairo Egypt.ORCID https://orcid.org/0000-0002-5543-9550
Nehal H ElghazawyDepartment of Chemistry, School of Sciences & Engineering, The American University in Cairo SSE, Rm #1194, P.O. Box 74 New Cairo 11835 Egypt hazzazy@aucegypt.edu.
Wolfgang FritzscheDepartment of Nanobiophotonics, Leibniz Institute for Photonic Technology Jena 07745 Germany.
Hassan M E AzzazyDepartment of Chemistry, School of Sciences & Engineering, The American University in Cairo SSE, Rm #1194, P.O. Box 74 New Cairo 11835 Egypt hazzazy@aucegypt.edu.ORCID https://orcid.org/0000-0003-2047-4222
Ain Shams University · EGLeibniz Institute of Photonic Technology · DEAmerican University in Cairo · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alzheimer's disease (AD) is the most common type of dementia and progresses from mild memory loss to severe decline in thinking, behavioral and social skills, which dramatically impairs a person's ability to function independently. Genetics, some health disorders and lifestyle have all been connected to AD. Also, environmental factors are reported as contributors to this illness. The presence of heavy metals in air, water, food, soil and commercial products has increased tremendously. Accumulation of heavy metals in the body leads to serious malfunctioning of bodily organs, specifically the brain. For AD, a wide range of heavy metals have been reported to contribute to its onset and progression and the manifestation of its hallmarks. In this review, we focus on detection of highly toxic heavy metals such as mercury, cadmium, lead and arsenic in water. The presence of heavy metals in water is very troubling and regular monitoring is warranted. Optical chemosensors were designed and fabricated for determination of ultra-trace quantities of heavy metals in water. They have shown advantages when compared to other sensors, such as selectivity, low-detection limit, fast response time, and wide-range determination under optimal sensing conditions. Therefore, implementing optical chemosensors for monitoring levels of toxic metals in water represents an important contribution in fighting AD.

Identifiers

PMID36425686
PMCPMC9664454
OpenAlexW4310334421

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.