Evidence map›Paper›PMID 36425636›Full record

ArticleBiomedical optics express2022

Using deep learning for the automated identification of cone and rod photoreceptors from adaptive optics imaging of the human retina.

Mengxi Zhou, Nathan Doble, Stacey S Choi, Tianyu Jin, Chenwei Xu, Srinivasan Parthasarathy, Rajiv Ramnath

Abstract read
In one paragraph

Article in Biomedical optics express, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mengxi ZhouThe Ohio State University, Department of Computer Science and Engineering, 2015 Neil Ave., Columbus, OH 43210, USA.ORCID https://orcid.org/0000-0002-8259-5874
Nathan DobleThe Ohio State University, College of Optometry, 338 W 10th Ave., Columbus, OH 43210, USA.
Stacey S ChoiThe Ohio State University, College of Optometry, 338 W 10th Ave., Columbus, OH 43210, USA.
Tianyu JinThe Ohio State University, Department of Computer Science and Engineering, 2015 Neil Ave., Columbus, OH 43210, USA.
Chenwei XuThe Ohio State University, Department of Statistics, 127 Pomerene Hall, 1760 Neil Ave, Columbus, OH 43212, USA.
Srinivasan ParthasarathyThe Ohio State University, Department of Computer Science and Engineering, 2015 Neil Ave., Columbus, OH 43210, USA.
Rajiv RamnathThe Ohio State University, Department of Computer Science and Engineering, 2015 Neil Ave., Columbus, OH 43210, USA.

Funding

The Ohio State University Vision Sciences Research Core Program (OSU-VSRCP)P30EY032857 · NEI · OHIO STATE UNIVERSITY · PI Sayoko E Moroi · 2022 to 2026
$3.6M
NEI NIH HHS P30 EY032857
6 · The paper itself

Abstract

Adaptive optics imaging has enabled the enhanced in vivo retinal visualization of individual cone and rod photoreceptors. Effective analysis of such high-resolution, feature rich images requires automated, robust algorithms. This paper describes RC-UPerNet, a novel deep learning algorithm, for identifying both types of photoreceptors, and was evaluated on images from central and peripheral retina extending out to 30° from the fovea in the nasal and temporal directions. Precision, recall and Dice scores were 0.928, 0.917 and 0.922 respectively for cones, and 0.876, 0.867 and 0.870 for rods. Scores agree well with human graders and are better than previously reported AI-based approaches.

Identifiers

PMID36425636
PMCPMC9664895

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.