Evidence map›Paper›PMID 36425603›Full record

ArticleIranian journal of veterinary research2022

A preliminary evaluation of tick cement-cone protein extract for a vaccine against

N Rafiq, M Naseem, A Kakar, J H Shirazi, M I Masood

Abstract read
In one paragraph

Article in Iranian journal of veterinary research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Tick Vaccines and Concealed versus Exposed Antigens.Pathogens (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

N RafiqDepartment of Zoology, SBK Women University, Quetta-87300, Pakistan.
M NaseemDepartment of Zoology, University of Balochistan, Quetta-87300, Pakistan.
A KakarDepartment of Zoology, University of Balochistan, Quetta-87300, Pakistan.
J H ShiraziDepartment of Pharmaceutics, Faculty of Pharmacy, The Islamia University of Bahawalpur-63100, Pakistan.
M I MasoodInstitute of Pharmaceutical Sciences, University of Veterinary and Animal Sciences Lahore-54000, Pakistan, and , and.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Vaccines have been widely exploited to prevent tick-borne infections in cattle. Most vaccines have faced failure in the field because of inconsistency in an immune response. It is presumed that the cement-cone proteins of ticks that participate in the acquisition of blood meal for ticks possess strong immune-stimulating properties and, hence, could be a useful candidate in vaccine development. Aims: We evaluated cement-cone proteins of tick Methods: The cement-cone proteins were extracted from Results: The findings of the present study demonstrated the cross-reactivity among the two species of ticks that belonged to the same genus ( Conclusion: The vaccine based upon cement-cone proteins of ticks may be a useful deterrent against tick-borne infections in cattle in countries like Pakistan.

Indexed as

CattleCement-coneCross-reactiveTickVaccine

Identifiers

PMID36425603
PMCPMC9681977

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.