Evidence map›Paper›PMID 36425580›Full record

ArticleFrontiers in pharmacology2022

Salvianolic acid A regulates pyroptosis of endothelial cells

Ji Zhu, Hang Chen, Yifei Le, Jianan Guo, Zhijun Liu, Xiaobing Dou, Dezhao Lu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 2 pooled it
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 2 syntheses or guidelines pooled it, 48 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. PKM2: A gatekeeper in macrophage metabolic reprogramming.Journal of pharmaceutical analysis · 2026
    Review
  4. Review
  5. Article
  6. Article
  7. Reviews in cardiovascular medicine · 2026
    Article
  8. Review
  9. Article
  10. Review
  11. Review
  12. Review
  13. Article
  14. Review
  15. Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Ji ZhuThe Third School of Clinical Medicine (School of Rehabilitation Medicine), Zhejiang Chinese Medical University, Hangzhou, China.
Hang ChenSchool of Life Sciences, Zhejiang Chinese Medical University, Hangzhou, China.
Yifei LeSchool of Life Sciences, Zhejiang Chinese Medical University, Hangzhou, China.
Jianan GuoSchool of Life Sciences, Zhejiang Chinese Medical University, Hangzhou, China.
Zhijun LiuSchool of Life Sciences, Zhejiang Chinese Medical University, Hangzhou, China.
Xiaobing DouSchool of Life Sciences, Zhejiang Chinese Medical University, Hangzhou, China.
Dezhao LuSchool of Life Sciences, Zhejiang Chinese Medical University, Hangzhou, China.
Zhejiang Chinese Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rescuing endothelial cells from pyroptotic cell death emerges as a potential therapeutic strategy to combat diabetic atherosclerosis. Salvianolic acid A (SAA) is a major water-soluble phenolic acid in the

Indexed as

diabetic atherosclerosisendothelial cellsPKM2pyroptosisSalvianolic acid A

Identifiers

PMID36425580
PMCPMC9679534
OpenAlexW4308591613

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.