Evidence map›Paper›PMID 36425554›Full record

ArticleFrontiers in oncology2022

Low-dose sclerotherapy with lauromacrogol in the treatment of infantile hemangiomas: A retrospective analysis of 368 cases.

Changfeng Wang, Jiali Sun, Lei Guo, Dan Song, Xin Zhang, Zhuang Liu, Liang Wang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Recent updates in laryngeal hemangioma management: a scoping review.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Changfeng WangDepartment of Vascular Anomalies and Interventional Radiology, Children's Hospital Affiliated to Shandong University, Jinan, Shandong, China.
Jiali SunDepartment of Vascular Anomalies and Interventional Radiology, Children's Hospital Affiliated to Shandong University, Jinan, Shandong, China.
Lei GuoDepartment of Vascular Anomalies and Interventional Radiology, Children's Hospital Affiliated to Shandong University, Jinan, Shandong, China.
Dan SongDepartment of Vascular Anomalies and Interventional Radiology, Children's Hospital Affiliated to Shandong University, Jinan, Shandong, China.
Xin ZhangDepartment of Vascular Anomalies and Interventional Radiology, Children's Hospital Affiliated to Shandong University, Jinan, Shandong, China.
Zhuang LiuDepartment of Vascular Anomalies and Interventional Radiology, Children's Hospital Affiliated to Shandong University, Jinan, Shandong, China.
Liang WangDepartment of Vascular Anomalies and Interventional Radiology, Children's Hospital Affiliated to Shandong University, Jinan, Shandong, China.
Shandong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Intralesional injection of lauromacrogol has proven to be an efficient treatment method for infantile hemangioma. This study aims to explore a novel injection therapy and evaluate its efficacy and complications. Methods: The medical records of 368 children with infantile hemangioma who received a lauromacrogol injection from January 2021 to April 2022 were retrospectively analyzed. All patients were reviewed every 4 weeks, and their condition was assessed according to symptoms and medical records. The patient's age, lesion type, location, size and thickness, lesion photographs, ultrasound, and complications were recorded. Results: Among the 368 infants who accept sclerotherapy with lauromacrogol, 226(61.4%)achieved excellent regression. In total, 108(29.4%)cases achieved good regression. 24(6.5%)achieved complete moderate regression. 10(2.7%)achieved poor regression. The reported incidence of adverse events was 4.9% and severe complications were not observed. Before and after three courses of treatment, the median vascular endothelial growth factor levels were 104.12 pg/ml and 28.982 pg/ml. There was a significant difference between the two groups (P=0.0043). Conclusions: The results showed that this novel injection therapy a safe and effective treatment method. The therapy accelerated the regression of infantile hemangiomas without serious complications.

Indexed as

infantile hemangiomaintralesional injectionlauromacrogol sclerotherapytreatmentvascular endothelial growth factor

Identifiers

PMID36425554
PMCPMC9681145
OpenAlexW4308424108

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.