Evidence map›Paper›PMID 36425456›Full record

ArticleBiophysical reports2021

On distributions of barrier crossing times as observed in single-molecule studies of biomolecules.

Alexander M Berezhkovskii, Dmitrii E Makarov

Abstract read
In one paragraph

Article in Biophysical reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Time and Length Scales of Incomplete Translocation through Nanopores.The journal of physical chemistry letters · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Alexander M BerezhkovskiiMathematical and Statistical Computing Laboratory, Office of Intramural Research, Center for Information Technology, National Institutes of Health, Bethesda, Maryland.
Dmitrii E MakarovDepartment of Chemistry and Biochemistry and Oden Institute for Computational Engineering and Sciences, University of Texas at Austin, Austin, Texas.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Single-molecule experiments that monitor time evolution of molecular observables in real time have expanded beyond measuring transition rates toward measuring distributions of times of various molecular events. Of particular interest is the first-passage time for making a transition from one molecular configuration (

Identifiers

PMID36425456
PMCPMC9680812

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.