Evidence map›Paper›PMID 36425424›Full record

ArticleHeliyon2022

The genetic legacy of the Hunyadi descendants.

Endre Neparáczki, Luca Kis, Zoltán Maróti, Bence Kovács, Gergely I B Varga, Miklós Makoldi, Pamjav Horolma, Éva Teiszler, Balázs Tihanyi, Péter L Nagy and 10 more

Open access · goldAbstract read
In one paragraph

Article in Heliyon, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 6 institutions in 3 countries.

Endre NeparáczkiDepartment of Archaeogenetics, Institute of Hungarian Research, Budapest, Hungary.
Luca KisDepartment of Archaeogenetics, Institute of Hungarian Research, Budapest, Hungary.
Zoltán MarótiDepartment of Archaeogenetics, Institute of Hungarian Research, Budapest, Hungary.
Bence KovácsDepartment of Archaeogenetics, Institute of Hungarian Research, Budapest, Hungary.
Gergely I B VargaDepartment of Archaeogenetics, Institute of Hungarian Research, Budapest, Hungary.
Miklós MakoldiDepartment of Archaeology, Institute of Hungarian Research, Budapest, Hungary.
Pamjav HorolmaInstitute of Forensic Genetics, Hungarian Institute for Forensic Sciences, Budapest, Hungary.
Éva TeiszlerDepartment of History, Institute of Hungarian Research, Budapest, Hungary.
Balázs TihanyiDepartment of Archaeogenetics, Institute of Hungarian Research, Budapest, Hungary.
Péter L NagyPraxis Genomics LLC, Atlanta, GA, USA.
Kitti MaárDepartment of Genetics, University of Szeged, Szeged, Hungary.
Attila GyeneseiGenomics and Bioinformatics Core Facility, Szentágothai Research Centre, University of Pécs, Pécs, Hungary.
Oszkár SchützDepartment of Genetics, University of Szeged, Szeged, Hungary.
Eszter DudásInstitute of Forensic Genetics, Hungarian Institute for Forensic Sciences, Budapest, Hungary.
Tibor TörökDepartment of Archaeogenetics, Institute of Hungarian Research, Budapest, Hungary.
Vesna Pascuttini-JuragaMinistry of Culture and Media, Conservation Department in Varaždin for the Areas of the Varaždin and Međimurje Counties, Varazdin, Croatia.
Ivančica PehardaMinistry of Culture and Media, Conservation Department in Varaždin for the Areas of the Varaždin and Međimurje Counties, Varazdin, Croatia.
László Tamás ViziDepartment of History, Institute of Hungarian Research, Budapest, Hungary.
Gábor Horváth-LugossyInstitute of Hungarian Research, Budapest, Hungary.
Miklós KáslerNational Institute of Oncology, Budapest, Hungary.
University of Szeged · HUOpća Bolnica Varaždin · HRHungarian Meat Research Institute · HUNational Institute of Oncology · HUPraxis (United States) · USUniversity of Pecs · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Hunyadi family is one of the most influential families in the history of Central Europe in the 14th-16th centuries. The family's prestige was established by Johannes Hunyadi, a Turk-beater who rose to the position of governor of the Kingdom of Hungary. His second son, Matthias Hunyadi, became the elected ruler of the Kingdom of Hungary in 1458. The Hunyadi family had unknown origin. Moreover, Matthias failed to found a dynasty because of lacking a legitimate heir and his illegitimate son Johannes Corvinus was unable to obtain the crown. His grandson, Christophorus Corvinus, died in childhood, thus the direct male line of the family ended. In the framework of on interdisciplinary research, we have determined the whole genome sequences of Johannes Corvinus and Christophorus Corvinus by next-generation sequencing technology. Both of them carried the Y-chromosome haplogroup is E1b1b1a1b1a6a1c ∼, which is widespread in Eurasia. The father-son relationship was verified using the classical STR method and whole genome data. Christophorus Corvinus belongs to the rare, sporadically occurring T2c1+146 mitochondrial haplogroup, most frequent around the Mediterranean, while his father belongs to the T2b mitochondrial haplogroup, widespread in Eurasia, both are consistent with the known origin of the mothers. Archaeogenomic analysis indicated that the Corvinus had an ancient European genome composition. Based on the reported genetic data, it will be possible to identify all the other Hunyadi family member, whose only known grave site is known, but who are resting assorted with several other skeletons.

Indexed as

Ancient genomesCorvinusHungarian Nobel familyHunyadi

Identifiers

PMID36425424
PMCPMC9678726
OpenAlexW4309552542

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.