Evidence map›Paper›PMID 36425408›Full record

ArticleHeliyon2022

The number of the intraepithelial T cells correlate with the proliferation index in human bulbourethral gland epithelium.

Tatiana Boronikhina, Gennadii Piavchenko, Artem Venediktov, Ekaterina Kustavinova, Svetlana Mukhamedova, Natalia Kartashkina, Sergey Kuznetsov, Igor Meglinski, Alexander Yatskovskiy

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Heliyon, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 58% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Gene Expression in Porcine Bulbourethral Glands.Animals : an open access journal from MDPI · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 3 countries.

Tatiana BoronikhinaDepartment of Histology, Cytology, and Embryology, I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia.
Gennadii PiavchenkoDepartment of Histology, Cytology, and Embryology, I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia.
Artem VenediktovDepartment of Histology, Cytology, and Embryology, I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia.
Ekaterina KustavinovaDepartment of Histology, Cytology, and Embryology, I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia.
Svetlana MukhamedovaDepartment of Histology, Cytology, and Embryology, I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia.
Natalia KartashkinaDepartment of Histology, Cytology, and Embryology, I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia.
Sergey KuznetsovDepartment of Histology, Cytology, and Embryology, I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia.
Igor MeglinskiOpto-Electronics and Measurement Techniques, Faculty of Information and Electrical Engineering, University of Oulu, Oulu, Finland.
Alexander YatskovskiyDepartment of Histology, Cytology, and Embryology, I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia.
Sechenov University · RUAston University · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Our study has immunohistochemically examined T cells localization and number as well as proliferative activity level for the bulbourethral gland epithelium in men of different ages, using monoclonal antibodies against CD45RO and proliferating cell nuclear antigen (PCNA). Results: We have found that the T cells have been localized mainly in excretory ducts epithelium of the glands in any age group, meanwhile their relative number varies with age. The excretory ducts epithelium has shown a high proliferative activity when in acini the PCNA index has been low. Postnatal dynamics of the epithelium proliferative activity positively correlates with age-related density fluctuations in lymphocytic infiltration of the glands. Conclusions: We consider that intraepithelial T cells may contribute to the regulation of epithelial cells proliferation in the bulbourethral glands.

Indexed as

Epithelial proliferationHuman bulbourethral glandsLymphocytic infiltrationProliferating cell nuclear antigenT cells

Identifiers

PMID36425408
PMCPMC9678671
OpenAlexW4309552682

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.