Evidence map›Paper›PMID 36425230›Full record

ArticleHealth psychology research2022

Phenothiazines and their Evolving Roles in Clinical Practice: A Narrative Review.

Amber N Edinoff, Grace Armistead, Christina A Rosa, Alexandra Anderson, Ronan Patil, Elyse M Cornett, Kevin S Murnane, Adam M Kaye, Alan D Kaye

Open access · goldAbstract read
In one paragraph

Article in Health psychology research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
4.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 32 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Amber N EdinoffDepartment of Psychiatry and Behavioral Medicine, Louisiana State University Health Shreveport.
Grace ArmisteadDepartment of Psychiatry and Behavioral Medicine, Louisiana State University Health Shreveport.
Christina A RosaDepartment of Psychology, University of California, Santa Barbara.
Alexandra AndersonSchool of Medicine, Louisiana State University Health Shreveport.
Ronan PatilSchool of Medicine, The George Washington University.
Elyse M CornettDepartment of Anesthesiology, Louisiana State University Health Shreveport.
Kevin S MurnaneDepartment of Psychiatry and Behavioral Medicine, Louisiana State University Health Shreveport; Louisiana State University Health Shreveport, Department of Pharmacology, Toxicology & Neuroscience; Louisiana Addiction Research Center.
Adam M KayeDepartment of Pharmacy Practice, Thomas J. Long School of Pharmacy, University of the Pacific, Stockton.
Alan D KayeDepartment of Anesthesiology, Louisiana State University Health Shreveport.
Louisiana State University · USLouisiana State University in Shreveport · USGeorge Washington University · USUniversity of California, Santa Barbara · USUniversity of the Pacific · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Phenothiazines, a diverse class of drugs, can be used to treat multiple mental health and physical conditions. Phenothiazines have been used for decades to treat mental illnesses, including schizophrenia, mania in bipolar disorder, and psychosis. Additionally, these drugs offer relief for physical illnesses, including migraines, hiccups, nausea, and vomiting in both adults and children. Further research is needed to prove the efficacy of phenothiazines in treating physical symptoms. Phenothiazines are dopaminergic antagonists that inhibit D2 receptors with varying potency. High potency phenothiazines such as perphenazine are used to treat various psychiatric conditions such as the positive symptoms of schizophrenia, the symptoms of psychosis, and mania that can occur with bipolar disorder. Low/mid potency phenothiazines such as chlorpromazine antipsychotic drugs that have been used to treat schizophrenia and schizophrenia-like disorders since the 1950s and are utilized in numerous disease states. The present investigation aims to elucidate the effects of phenothiazines in clinical practice.

Indexed as

adverse effectschlorpromazinehiccupsmigrainesnausea and vomitingperphenazinePhenothiazines

Identifiers

PMID36425230
PMCPMC9680852
OpenAlexW4309784830

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.