ArticleBiophysical reports2022
Molecular understanding of calorimetric protein unfolding experiments.
Article in Biophysical reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed.
- pH-Dependent Stability and Cooperativity of Protein Unfolding from Differential Scanning Calorimetry Using FitFoldData.Biomolecules · 2026Article
- How Does Genetic Information Enable Life?Bulletin of mathematical biology · 2026Article
- Exploring Different Extrapolation Approaches for the Critical Temperature of the 2D-Ising Model Based on Exactly Solvable Finite-Sized Lattices.Entropy (Basel, Switzerland) · 2025Article
- Preserving enzyme conformation and catalytic efficiency in crowded and active environments.Nanoscale advances · 2025Article
- Article
- Pressure Protein Denaturation Compared to Thermal and Chemical Unfolding: Analyses with Cooperative Models.The journal of physical chemistry. B · 2025Article
- Article
- Chemical Protein Unfolding - A Simple Cooperative Model.The journal of physical chemistry. B · 2023Article
- Protein Stability─Analysis of Heat and Cold Denaturation without and with Unfolding Models.The journal of physical chemistry. B · 2023Article
- Protein Unfolding-Thermodynamic Perspectives and Unfolding Models.International journal of molecular sciences · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Testing and predicting protein stability gained importance because proteins, including antibodies, became pharmacologically relevant in viral and cancer therapies. Isothermal scanning calorimetry is the principle method to study protein stability. Here, we use the excellent experimental heat capacity C
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.