Evidence map›Paper›PMID 36425073›Full record

ArticleFrontiers in genetics2022

Structure and evolution of the squamate major histocompatibility complex as revealed by two

Daren C Card, Andrew G Van Camp, Trenten Santonastaso, Michael I Jensen-Seaman, Nicola M Anthony, Scott V Edwards

Open access · goldAbstract read
In one paragraph

Article in Frontiers in genetics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 11 citations in OpenAlex.

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  10. Genome Evolution and the Future of Phylogenomics of Non-Avian Reptiles.Animals : an open access journal from MDPI · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Daren C CardDepartment of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA, United States.
Andrew G Van CampDepartment of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA, United States.
Trenten SantonastasoDepartment of Biological Sciences, University of New Orleans, New Orleans, LA, United States.
Michael I Jensen-SeamanDepartment of Biological Sciences, Duquesne University, Pittsburgh, PA, United States.
Nicola M AnthonyDepartment of Biological Sciences, University of New Orleans, New Orleans, LA, United States.
Scott V EdwardsDepartment of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA, United States.
Harvard University · USUniversity of New Orleans · USDuquesne University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The major histocompatibility complex (MHC) is an important genomic region for adaptive immunity and has long been studied in ecological and evolutionary contexts, such as disease resistance and mate and kin selection. The MHC has been investigated extensively in mammals and birds but far less so in squamate reptiles, the third major radiation of amniotes. We localized the core MHC genomic region in two squamate species, the green anole (

Indexed as

BAC sequencingcomparative genomicsimmunityMHCnatural selectionsquamata

Identifiers

PMID36425073
PMCPMC9679377
OpenAlexW4308595121

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.