Evidence map›Paper›PMID 36425042›Full record

ArticleFrontiers in microbiology2022

Enrichment of antibiotic resistance genes within bacteriophage populations in saliva samples from individuals undergoing oral antibiotic treatments.

Tilde Andersson, Geofrey Makenga, Filbert Francis, Daniel T R Minja, Soren Overballe-Petersen, Man-Hung Eric Tang, Kurt Fuursted, Vito Baraka, Rolf Lood

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Tilde AnderssonDepartment of Clinical Sciences, Lund University, Lund, Sweden.
Geofrey MakengaNational Institute for Medical Research, Tanga Center, Tanzania.
Filbert FrancisNational Institute for Medical Research, Tanga Center, Tanzania.
Daniel T R MinjaNational Institute for Medical Research, Tanga Center, Tanzania.
Soren Overballe-PetersenBacterial Reference Center, Statens Serum Institute, Copenhagen, Denmark.
Man-Hung Eric TangDepartment of Bacteria, Parasites and Fungi, Statens Serum Institut, Copenhagen, Denmark.
Kurt FuurstedBacterial Reference Center, Statens Serum Institute, Copenhagen, Denmark.
Vito BarakaNational Institute for Medical Research, Tanga Center, Tanzania.
Rolf LoodDepartment of Clinical Sciences, Lund University, Lund, Sweden.
National Institute for Medical Research · TZStatens Serum Institut · DKLund University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spread of antibiotic resistance is a significant challenge for our modern health care system, and even more so in developing countries with higher prevalence of both infections and resistant bacteria. Faulty usage of antibiotics has been pinpointed as a driving factor in spread of resistant bacteria through selective pressure. However, horizontal gene transfer mediated through bacteriophages may also play an important role in this spread. In a cohort of Tanzanian patients suffering from bacterial infections, we demonstrate significant differences in the oral microbial diversity between infected and non-infected individuals, as well as before and after oral antibiotics treatment. Further, the resistome carried both by bacteria and bacteriophages vary significantly, with

Indexed as

antibiotic resistanceantibiotic treatmentBacteriophagemicrobiotasaliva

Identifiers

PMID36425042
PMCPMC9678940
OpenAlexW4308594594

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.