Evidence map›Paper›PMID 36424655›Full record

ArticleChild and adolescent psychiatry and mental health2022

Evidence of individual differences in the long-term social, psychological, and cognitive consequences of child maltreatment.

Rosa S Wong, Keith T S Tung, Ko Ling Chan, Wilfred H S Wong, Hing Wai Tsang, Clare H Y Chow, Gilbert T Chua, Winnie W Y Tso, Jason C Yam, Ian C K Wong and 1 more

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Article in Child and adolescent psychiatry and mental health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Rosa S WongDepartment of Paediatrics and Adolescent Medicine, The University of Hong Kong, Hong Kong, SAR, China.
Keith T S TungDepartment of Paediatrics and Adolescent Medicine, The University of Hong Kong, Hong Kong, SAR, China.
Ko Ling ChanDepartment of Applied Social Sciences, The Hong Kong Polytechnic University, Hong Kong, SAR, China.
Wilfred H S WongDepartment of Paediatrics and Adolescent Medicine, The University of Hong Kong, Hong Kong, SAR, China.
Hing Wai TsangDepartment of Paediatrics and Adolescent Medicine, The University of Hong Kong, Hong Kong, SAR, China.
Clare H Y ChowDepartment of Paediatrics and Adolescent Medicine, The University of Hong Kong, Hong Kong, SAR, China.
Gilbert T ChuaDepartment of Paediatrics and Adolescent Medicine, The University of Hong Kong, Hong Kong, SAR, China.
Winnie W Y TsoDepartment of Paediatrics and Adolescent Medicine, The University of Hong Kong, Hong Kong, SAR, China.
Jason C YamDepartment of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong, SAR, China.
Ian C K WongDepartment of Pharmacology and Pharmacy, The University of Hong Kong, Hong Kong, SAR, China.
Patrick LpDepartment of Paediatrics and Adolescent Medicine, The University of Hong Kong, Hong Kong, SAR, China. patricip@hku.hk.

Funding

Research Grants Council, University Grants Committee General Research Fund, Project No. 17620919
6 · The paper itself

Abstract

backgroundThe prevalence and consequences of child maltreatment are alarming, but evidence from studies with long follow-up intervals are limited. This study examined the long-term consequences of child maltreatment in relation to age of onset and follow-up interval.

methodsThe exposed group comprised 63 individuals (aged 13-34 years) with a first-time diagnosis of child maltreatment between 2001 and 2010, whereas the unexposed group comprised 63 individuals who were matched upon gender, age of onset, follow-up period, and poverty status at the index hospital admission but had no medical records of maltreatment in Hong Kong. The participants completed a set of questionnaires on executive functions and mental health and provided blood samples for measurement of IL-6 and IL-10 levels during a health assessment session.

resultsCompared with the unexposed group, the exposed group reported poorer maternal care during childhood (β = -4.64, p < 0.001) and had lower family support (β = -2.97, p = 0.010) and higher inflammatory responses (IL-6: β = 0.15, p = 0.001; IL-10: β = 0.11, p = 0.011) at follow-up. Additionally, the associations of childhood maltreatment exposure with family support and maternal care differed by age of onset and the length of time since exposure.

conclusionsThis matched cohort study highlights childhood maltreatment as a risk factor for systemic inflammation and an indicator of suboptimal social environment, both of which could persist over a long period of time.

Indexed as

AdulthoodChild maltreatmentCytokineFamily supportInflammationStress

Identifiers

PMID36424655
PMCPMC9686092

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.