Evidence map›Paper›PMID 36424647›Full record

ArticleAntimicrobial resistance and infection control2022

Effect of temperature on Escherichia coli bloodstream infection in a nationwide population-based study of incidence and resistance.

Sarah F Feldman, Elizabeth Temkin, Liat Wulffhart, Amir Nutman, Vered Schechner, Pnina Shitrit, Racheli Shvartz, Mitchell J Schwaber, Yehuda Carmeli

Abstract read
In one paragraph

Article in Antimicrobial resistance and infection control, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Climate change and antimicrobial resistance.Nature reviews. Microbiology · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sarah F FeldmanNational Institute for Antibiotic Resistance and Infection Control, Ministry of Health, Tel Aviv, Israel.
Elizabeth TemkinNational Institute for Antibiotic Resistance and Infection Control, Ministry of Health, Tel Aviv, Israel.
Liat WulffhartNational Institute for Antibiotic Resistance and Infection Control, Ministry of Health, Tel Aviv, Israel.
Amir NutmanNational Institute for Antibiotic Resistance and Infection Control, Ministry of Health, Tel Aviv, Israel.
Vered SchechnerNational Institute for Antibiotic Resistance and Infection Control, Ministry of Health, Tel Aviv, Israel.
Pnina ShitritSackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Racheli ShvartzNational Institute for Antibiotic Resistance and Infection Control, Ministry of Health, Tel Aviv, Israel.
Mitchell J SchwaberNational Institute for Antibiotic Resistance and Infection Control, Ministry of Health, Tel Aviv, Israel.
Yehuda CarmeliNational Institute for Antibiotic Resistance and Infection Control, Ministry of Health, Tel Aviv, Israel. yehudac@tlvmc.gov.il.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe incidence of Escherichia coli bloodstream infections (BSI) is high and increasing. We aimed to describe the effect of season and temperature on the incidence of E. coli BSI and antibiotic-resistant E. coli BSI and to determine differences by place of BSI onset.

methodsAll E. coli BSI in adult Israeli residents between January 1, 2018 and December 19, 2019 were included. We used the national database of mandatory BSI reports and outdoor temperature data. Monthly incidence and resistance were studied using multivariable negative binomial regressions with season (July-October vs. other) and temperature as covariates.

resultsWe included 10,583 events, 9012 (85%) community onset (CO) and 1571 (15%) hospital onset (HO). For CO events, for each average monthly temperature increase of 5.5 °C, the monthly number of events increased by 6.2% (95% CI 1.6-11.1%, p = 0.008) and the monthly number of multidrug-resistant events increased by 4.9% (95% CI 0.3-9.7%, p = 0.04). The effect of season was not significant. For HO events, incidence of BSI and resistant BSI were not associated with temperature or season.

conclusionTemperature increases the incidence of CO E. coli BSI and CO antibiotic-resistant E. coli BSI. Global warming threatens to increase the incidence of E. coli BSI.

Indexed as

BacteremiaEscherichia coli InfectionsAdultAnti-Bacterial AgentsEscherichia coliHumansIncidenceTemperatureAnti-Bacterial AgentsAntibiotic resistanceBloodstream infectionEpidemiologyEscherichia coliSeasonal variationTemperature

Identifiers

PMID36424647
PMCPMC9685946

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.