Evidence map›Paper›PMID 36424621›Full record

ArticleAIDS research and therapy2022

Impact of antiretroviral therapy (ART) duration on ART adherence among men who have sex with men (MSM) living with HIV in Jinan of China.

Kedi Jiao, Meizhen Liao, Guangmei Liu, Yanmei Bi, Xiuhong Zhao, Qian Chen, Jing Ma, Yu Yan, Chunxiao Cheng, Yijun Li and 11 more

Abstract read
In one paragraph

Article in AIDS research and therapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Kedi JiaoDepartment of Epidemiology, School of Public Health, Cheeloo College of Medicine, Shandong University, 44 West Wenhua Road, Jinan, 250012, Shandong, People's Republic of China.
Meizhen LiaoInstitution for AIDS/STD Control and Prevention, Shandong Center for Disease Control and Prevention, 16992 Jingshi Road, Jinan, 250014, Shandong, People's Republic of China.
Guangmei LiuShandong Public Health Clinical Center, 12 East Martyrs Mountain Road, Jinan, 250132, Shandong, People's Republic of China.
Yanmei BiShandong Public Health Clinical Center, 12 East Martyrs Mountain Road, Jinan, 250132, Shandong, People's Republic of China.
Xiuhong ZhaoShandong Public Health Clinical Center, 12 East Martyrs Mountain Road, Jinan, 250132, Shandong, People's Republic of China.
Qian ChenShandong Public Health Clinical Center, 12 East Martyrs Mountain Road, Jinan, 250132, Shandong, People's Republic of China.
Jing MaDepartment of Epidemiology, School of Public Health, Cheeloo College of Medicine, Shandong University, 44 West Wenhua Road, Jinan, 250012, Shandong, People's Republic of China.
Yu YanDepartment of Epidemiology, School of Public Health, Cheeloo College of Medicine, Shandong University, 44 West Wenhua Road, Jinan, 250012, Shandong, People's Republic of China.
Chunxiao ChengDepartment of Epidemiology, School of Public Health, Cheeloo College of Medicine, Shandong University, 44 West Wenhua Road, Jinan, 250012, Shandong, People's Republic of China.
Yijun LiDepartment of Epidemiology, School of Public Health, Cheeloo College of Medicine, Shandong University, 44 West Wenhua Road, Jinan, 250012, Shandong, People's Republic of China.
Wenwen JiaDepartment of Epidemiology, School of Public Health, Cheeloo College of Medicine, Shandong University, 44 West Wenhua Road, Jinan, 250012, Shandong, People's Republic of China.
Lina WangDepartment of Epidemiology, School of Public Health, Cheeloo College of Medicine, Shandong University, 44 West Wenhua Road, Jinan, 250012, Shandong, People's Republic of China.
Yanwen CaoDepartment of Epidemiology, School of Public Health, Cheeloo College of Medicine, Shandong University, 44 West Wenhua Road, Jinan, 250012, Shandong, People's Republic of China.
Zhonghui ZhaoDepartment of Epidemiology, School of Public Health, Cheeloo College of Medicine, Shandong University, 44 West Wenhua Road, Jinan, 250012, Shandong, People's Republic of China.
Xuan YangDepartment of Epidemiology, School of Public Health, Cheeloo College of Medicine, Shandong University, 44 West Wenhua Road, Jinan, 250012, Shandong, People's Republic of China.
Jing MengDepartment of Epidemiology, School of Public Health, Cheeloo College of Medicine, Shandong University, 44 West Wenhua Road, Jinan, 250012, Shandong, People's Republic of China.
Jianzhuo LiInstitution for AIDS/STD Control and Prevention, Jinan Center for Disease Control and Prevention, 2 Weiliu Road, Jinan, 250021, Shandong, People's Republic of China.
Xinrui LiInstitution for AIDS/STD Control and Prevention, Jinan Center for Disease Control and Prevention, 2 Weiliu Road, Jinan, 250021, Shandong, People's Republic of China.
Chunmei WangShandong Public Health Clinical Center, 12 East Martyrs Mountain Road, Jinan, 250132, Shandong, People's Republic of China. 2625099605@qq.com.
Dianmin KangInstitution for AIDS/STD Control and Prevention, Shandong Center for Disease Control and Prevention, 16992 Jingshi Road, Jinan, 250014, Shandong, People's Republic of China. dmkang66@163.com.
Wei MaDepartment of Epidemiology, School of Public Health, Cheeloo College of Medicine, Shandong University, 44 West Wenhua Road, Jinan, 250012, Shandong, People's Republic of China. weima@sdu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundConsistent and complete adherence is considered an essential requirement for patients on antiretroviral therapy (ART). This study aimed to evaluate the impact of ART duration on ART adherence, identify the trend of complete adherence, and compare the factors associated with ART adherence between short-term and long-term ART group among men who have sex with men (MSM) living with HIV in Jinan of China.

methodsMSM living with HIV aged 18 or above and currently on ART were recruited from October to December 2020 using convenience sampling. Univariate and multivariable logistic regressions were used to evaluate the impact of ART duration on adherence and compare factors associated with ART adherence between subgroups. The Mann-Kendall test was used to identify the trend of complete adherence.

resultsA total of 585 participants were included in analysis, consisting of 352 on short-term ART (ART initiation ≤ 3 years) and 233 on long-term ART (ART initiation > 3 years). Significant difference of complete ART adherence between short-term and long-term ART group was detected (79.8% vs. 69.1%, P = 0.003). Multivariable analysis showed that men with longer ART duration were less likely to report complete ART adherence (AOR = 0.88, 95% CI 0.81-0.95). A descending trend of complete adherence was identified (Z = 1.787, P = 0.037). Alcohol use and lack of medication reminders were barriers to complete adherence for both of the subgroups.

conclusionsSustained efforts to encourage maintaining adherence for a lifetime are necessary, especially for those on long-term ART. Future interventions should be tailored to subgroups with different ART duration and individuals with specific characteristics.

Indexed as

HIV InfectionsSexual and Gender MinoritiesAnti-Retroviral AgentsChinaHomosexuality, MaleHumansMaleAnti-Retroviral AgentsAntiretroviral therapy adherenceAntiretroviral therapy durationChinaMen who have sex with men

Identifiers

PMID36424621
PMCPMC9694540

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.