Evidence map›Paper›PMID 36424605›Full record

ArticleJournal of nanobiotechnology2022

Intravital electrochemical nanosensor as a tool for the measurement of reactive oxygen/nitrogen species in liver diseases.

Tatiana Abakumova, Alexander Vaneev, Victor Naumenko, Arina Shokhina, Vsevolod Belousov, Arsen Mikaelyan, Kamilla Balysheva, Peter Gorelkin, Alexander Erofeev, Timofei Zatsepin

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of nanobiotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 9 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Tatiana Abakumova *Skolkovo Institute of Science and Technology, Bolshoy Boulevard, 30/1, Moscow, 121205, Russia. sandalovato@gmail.com.
Alexander Vaneev *National University of Science and Technology «MISIS», Leninskiy Avenue, 4, Moscow, 119049, Russia. vaneev.aleksandr@gmail.com.
Victor NaumenkoV. Serbsky National Medical Research Center for Psychiatry and Narcology, Kropotkinskii Lane, 23, Moscow, 117034, Russia.
Arina ShokhinaFederal Center of Brain Research and Neurotechnologies of the Federal Medical Biological Agency, Ostrovityanova Street, 1/10, Moscow, 117513, Russia.
Vsevolod BelousovFederal Center of Brain Research and Neurotechnologies of the Federal Medical Biological Agency, Ostrovityanova Street, 1/10, Moscow, 117513, Russia.
Arsen MikaelyanKoltzov Institute of Developmental Biology of Russian Academy of Sciences, Vavilova Street, 26, Moscow, 119334, Russia.
Kamilla BalyshevaNational University of Science and Technology «MISIS», Leninskiy Avenue, 4, Moscow, 119049, Russia.
Peter GorelkinNational University of Science and Technology «MISIS», Leninskiy Avenue, 4, Moscow, 119049, Russia.
Alexander ErofeevNational University of Science and Technology «MISIS», Leninskiy Avenue, 4, Moscow, 119049, Russia.
Timofei ZatsepinLomonosov Moscow State University, Leninskie Gory, Moscow, 119991, Russia.
Federal Medical-Biological Agency · RULomonosov Moscow State University · RUNational University of Science and Technology · RUFederal Medical Research Centre for Psychiatry and Narcology · RUKoltzov Institute of Developmental Biology · RU

Funding

Council on grants of the President of the Russian Federation MK-1128.2020.4Russian Science Foundation 19-44-04111Russian Science Foundation 19-79-30062Russian Science Foundation 20-74-00116
6 · The paper itself

Abstract

Reactive oxygen/nitrogen species (ROS/RNS) are formed during normal cellular metabolism and contribute to its regulation, while many pathological processes are associated with ROS/RNS imbalances. Modern methods for measuring ROS/RNS are mainly based on the use of inducible fluorescent dyes and protein-based sensors, which have several disadvantages for in vivo use. Intravital electrochemical nanosensors can be used to quantify ROS/RNS with high sensitivity without exogenous tracers and allow dynamic ROS/RNS measurements in vivo. Here, we developed a method for quantifying total ROS/RNS levels in the liver and evaluated our setup in live mice using three common models of liver disease associated with ROS activation: acute liver injury with CCl

Indexed as

Carcinoma, HepatocellularLiver NeoplasmsAnimalsMiceNitrogenOxygenReactive Nitrogen SpeciesReactive Oxygen SpeciesNitrogenOxygenReactive Nitrogen SpeciesReactive Oxygen SpeciesElectrochemical detectionHepatocellular carcinomaIntravital imagingLiver diseaseNanosensorsOxidative stress

Identifiers

PMID36424605
PMCPMC9694853
OpenAlexW4309900083

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.