Evidence map›Paper›PMID 36424531›Full record

ArticleBMC pregnancy and childbirth2022

Incidence and determinants of maternal sepsis in Ghana in the midst of a pandemic.

Charles Lwanga Noora, Adom Manu, Adolphina Addo-Lartey, Abdul Gafaru Mohammed, Donne Kofi Ameme, Ernest Kenu, Kwasi Torpey, Richard Adanu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC pregnancy and childbirth, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Charles Lwanga NooraDepartment of Epidemiology, School of Public Health, College of Health Sciences, University of Ghana Legon, Accra, Ghana. nooralwanga@gmail.com.
Adom ManuDepartment of Population, Family and Reproductive Health, School of Public Health, College of Health Sciences, University of Ghana Legon, Accra, Ghana.
Adolphina Addo-LarteyDepartment of Epidemiology, School of Public Health, College of Health Sciences, University of Ghana Legon, Accra, Ghana.
Abdul Gafaru MohammedDepartment of Epidemiology, School of Public Health, College of Health Sciences, University of Ghana Legon, Accra, Ghana.
Donne Kofi AmemeDepartment of Epidemiology, School of Public Health, College of Health Sciences, University of Ghana Legon, Accra, Ghana.
Ernest KenuDepartment of Epidemiology, School of Public Health, College of Health Sciences, University of Ghana Legon, Accra, Ghana.
Kwasi TorpeyDepartment of Population, Family and Reproductive Health, School of Public Health, College of Health Sciences, University of Ghana Legon, Accra, Ghana.
Richard AdanuDepartment of Population, Family and Reproductive Health, School of Public Health, College of Health Sciences, University of Ghana Legon, Accra, Ghana.
University of Ghana · GH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDespite being preventable, maternal sepsis continues to be a significant cause of death and morbidity, killing one in every four pregnant women globally. In Ghana, clinicians have observed that maternal sepsis is increasingly becoming a major contributor to maternal mortality. The lack of a consensus definition for maternal sepsis before 2017 created a gap in determining global and country-specific burden of maternal sepsis and its risk factors. This study determined the incidence and risk factors of clinically proven maternal sepsis in Ghana.

methodsWe conducted a prospective cohort study among 1476 randomly selected pregnant women in six health facilities in Ghana, from January to September 2020. Data were collected using primary data collection tools and reviewing the client's charts. We estimated the incidence rate of maternal sepsis per 1,000 pregnant women per person-week. Poisson regression model and the cox-proportional hazard regression model estimators were used to assess risk factors associated with the incidence of maternal sepsis at a 5% significance level.

resultsThe overall incidence rate of maternal sepsis was 1.52 [95% CI: 1.20-1.96] per 1000 person-weeks. The majority of the participants entered the study at 10-13 weeks of gestation. The study participants' median body mass index score was 26.4 kgm

conclusionsOur findings show a low incidence of maternal sepsis in Ghana compared to most Low and Middle-Income Countries. Nonetheless, Maternal sepsis remains an important contributor to the overall maternal mortality burden. It is essential clinicians pay more attention to ensure early and prompt diagnosis. Factors significantly predicting maternal sepsis in Ghana were additional maternal morbidity, urinary tract infections, dysuria, and multiple symptoms. We recommend that Ghana Health Service should institute a surveillance system for maternal sepsis as a monthly reportable disease.

Indexed as

Pre-EclampsiaPregnancy Complications, InfectiousSepsisCesarean SectionFemaleGhanaHumansIncidencePandemicsPregnancyProspective StudiesGhanaIncidence rateMaternal mortalityMaternal sepsisPuerperal sepsis

Identifiers

PMID36424531
PMCPMC9686217
OpenAlexW4309923230

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.