Evidence map›Paper›PMID 36424455›Full record

ArticleExperimental & molecular medicine2022

Protective effect of hepatocyte-enriched lncRNA-Mir122hg by promoting hepatocyte proliferation in acute liver injury.

Zhenjun Yu, Yuhan Li, Shuai Shao, Beichen Guo, Mengxia Zhang, Lina Zheng, Kun Zhang, Feng Zhou, Li Zhang, Chiyi Chen and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Experimental & molecular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Deciphering the role ofWorld journal of hepatology · 2025
    Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Zhenjun Yu *Department of Hepatology and Gastroenterology, The Third Central Clinical College of Tianjin Medical University; Department of Histology and Embryology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China.ORCID 0000-0002-9456-7950
Yuhan Li *Department of Hepatology and Gastroenterology, The Third Central Clinical College of Tianjin Medical University; Department of Histology and Embryology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China.
Shuai Shao *Department of Gastroenterology and Hepatology, Tianjin Union Medical Center, Tianjin Medical University, Tianjin, China.
Beichen GuoDepartment of Hepatology and Gastroenterology, The Third Central Clinical College of Tianjin Medical University; Department of Histology and Embryology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China.
Mengxia ZhangDepartment of Histology and Embryology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China.
Lina ZhengDepartment of Histology and Embryology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China.
Kun ZhangDepartment of Histology and Embryology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China.
Feng ZhouDepartment of Hepatology and Gastroenterology, The Third Central Clinical College of Tianjin Medical University; Department of Histology and Embryology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China.
Li ZhangLiver transplant department, Organ transplant center, Tianjin First Center Hospital, Tianjin, China.
Chiyi ChenLiver transplant department, Organ transplant center, Tianjin First Center Hospital, Tianjin, China.
Wentao JiangLiver transplant department, Organ transplant center, Tianjin First Center Hospital, Tianjin, China. jiangwentao@vip.163.com.
Wei HongDepartment of Histology and Embryology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China. hongwei@tmu.edu.cn.
Tao HanDepartment of Hepatology and Gastroenterology, The Third Central Clinical College of Tianjin Medical University; Department of Histology and Embryology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China. hantaomd@126.com.ORCID 0000-0003-4216-6968
Tianjin Medical University · CNTianjin First Center Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Some long noncoding RNAs (lncRNAs), which harbor microRNAs in their gene sequence and are also known as microRNA host gene derived lncRNAs (lnc-MIRHGs), play a dominant role alongside miRNAs, or both perform biological functions synergistically or independently. However, only a small number of lnc-MIRHGs have been identified. Here, multiple liver injury datasets were analyzed to screen and identify the target lncRNA Mir122hg. Mir122hg was mainly enriched in liver tissues with human-mouse homology. In both CCl

Indexed as

MicroRNAsRNA, Long NoncodingAnimalsCell ProliferationGlycogen Synthase Kinase 3 betaHepatocytesHumansLiverMiceProto-Oncogene Proteins c-aktGlycogen Synthase Kinase 3 betaMicroRNAsProto-Oncogene Proteins c-aktRNA, Long Noncoding

Identifiers

PMID36424455
PMCPMC9722683
OpenAlexW4309865489

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.