Evidence map›Paper›PMID 36424102›Full record

ArticleBMJ open2022

Burden of active pulmonary tuberculosis among patients with diabetes in Dar es Salaam, Tanzania: a cross-sectional study.

Gerald Jamberi Makuka, Emmanuel Balandya, Patricia Munseri

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Article in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

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4citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Gerald Jamberi Makuka *Department of Internal Medicine, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania geraldmakuka@gmail.com.ORCID 0000-0002-1589-1999
Emmanuel Balandya *Department of Physiology, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania.
Patricia MunseriDepartment of Internal Medicine, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania.ORCID 0000-0002-8754-2755

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesWe aimed to determine the prevalence, associated factors and describe the chest radiographic findings for active pulmonary tuberculosis (TB) among patients with diabetes mellitus (DM) attending a diabetic clinic in Tanzania.

designCross-sectional study.

settingA diabetic clinic at Temeke Regional Referral Hospital in Dar es salaam, Tanzania.

participantsPatients with diabetes.

main outcome measuresThe prevalence and factors associated with active TB in patients with DM.

resultsAmong 623 patients with DM screened, 11 (1.8%); 95% CI 0.9 to 3.1, had active TB of which 6 (54.5%) were GeneXpert positive and 5 (45.5%) were diagnosed based on clinical symptoms and suggestive chest radiographs. The risk of active TB was lower in patients aged 45-64 years compared with age below 45 years (adjusted prevalence ratio (aPR) 0.39, 95% CI (0.11 to 0.42), p=0.001) and in patients with normal chest examination findings compared with patients with crackles or bronchial breathing sounds (aPR 0.02, 95% CI (0.01 to 0.15), p<0.01). The predominant chest radiographic findings were opacification 100% mainly in the upper and mid-lung zones.

conclusionDiabetics should be screened for pulmonary TB, particularly among individuals aged 45 years and below with crackles or bronchial breathing on auscultation of the chest. High index of suspicion could help in the early detection and control of TB.

Indexed as

Diabetes MellitusTuberculosisTuberculosis, PulmonaryCross-Sectional StudiesHumansLungRespiratory SoundsTanzaniageneral diabetesrespiratory infectionstuberculosis

Identifiers

PMID36424102
PMCPMC9693890

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